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Research Technician - Pediatric Oncology, Crompton Lab
Laboratory Overview: The Crompton laboratory uses a combination of next-generation sequencing and proteomic approaches to profile tumor material from matched tumor biopsies, circulating tumor DNA, and circulating tumor cells, isolated from both mouse models and patient samples. These studies are focused on understanding the genomic, proteomic, and epigenomic heterogeneity and disease evolution of pediatric solid tumors and leveraging that understanding to develop new pharmacodynamic markers of drug activity and discover mechanisms of treatment resistance. The laboratory works with an extensive network of clinical investigators running multi-institutional clinical trials from which well-annotated patient samples are obtained. The laboratory is well supported by Nati
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