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Postdoctoral Associates, El-Deiry Lab, Brown University
The EL-DEIRY LABORATORY, also known as the Laboratory of Translational Oncology and Experimental Cancer Therapeutics is a basic and translational cancer biology lab focused on tumor suppressor p53, extrinsic (TRAIL) and mitochondrial cell death pathways, drug discovery and development for cancer, and mechanisms of therapeutic resistance including under hypoxia. The training provides opportunity to develop an independent research project in the area of cell death mechanisms with novel cancer therapeutic agents. Studies will be focused on signaling mechanisms, molecular target validation, interactions with immune agents and mechanisms and use of in vivo mouse models and organoids. We are applying genomics, proteomics, epigenetics, high resolution molecular imaging and single cell
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