The Cammarato Lab is located in the Division of Cardiology in the Department of Medicine at The Johns Hopkins University School of Medicine. We are interested in basic mechanisms of striated muscle biology. Our group employs an array of imaging and analysis techniques to study “structural physiology” of cardiac and skeletal muscle from vertebrate (e.g. rodent, human engineered heart tissue) and invertebrate (i.e. Drosophila melanogaster) models. We study conserved myopathic processes and perform hierarchical and integrative analysis of muscle function from the level of single molecules and macromolecular complexes through the level of the tissue itself. For examples of recent projects and our general approach, please see: (1) Viswanathan, M.C., et al. "A role for actin flexibility in th
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