Position Description

The Simons Center for Quantitative Biology is pioneering the next generation of AI-driven biological research by creating a dynamic collaboration between experimental genomics and cutting-edge machine learning models. Our vision is to transform our understanding of gene regulation and unlock new frontiers in synthetic biology, drug discovery, and personalized medicine through rapid, iterative cycles of experimentation and AI model development. We are seeking applications for the position of Research Technician.

Position Responsibilities

Successful candidates will join a collaborative team of quantitative biologists (led by Dr. Peter Koo) and functional genomics scientists (led by Dr. Kenneth Chang). In these roles, you will design and conduct large-scale functional genomic experiments, including:

• Massively parallel reporter assays (MPRAs)
• Protein deep mutational scanning (DMS) assays
• CRISPR interference (CRISPRi) screens
• Genomic base-editing screens

 
These experiments will be directly tied to AI model development, helping to generate data that trains and refines next-generation AI models. Unlike traditional wet-lab roles, these positions offer the opportunity to directly contribute to the development of cutting-edge AI models, fostering a unique integration of experimentation and computation.
 
Additionally, you will collaborate with and support other scientists at CSHL, executing functional genomics experiments to meet a diverse array of research needs, with a focus on accelerating AI-driven discoveries. 

 

Position Requirements

Required: Bachelor's degree or equivalent in molecular biology, biochemistry, cell biology, or related biological discipline.
Preferred: Experience in molecular cloning and mammalian cell culture Familiarity with genetic screens, such as MPRAs. Interest in learning about AI modeling
 
What We Offer:

• A dynamic, collaborative environment at the intersection of cutting-edge genomics and machine learning research.
• Training in advanced genome-scale screening techniques and the chance to work on high-impact, innovative AI projects.
• Opportunities to collaborate directly with AI experts on groundbreaking research.
• A long-term vision of revolutionizing biology and medicine through AI-driven genomics.

 

Supplemental Information

How to Apply:
Join us in shaping the future of AI-driven biology and be part of a groundbreaking initiative that bridges the experimental and computational worlds at Cold Spring Harbor Laboratory! Please submit an online application here: Research Technician Position: 01805. We look forward to reviewing your application.

Environment
Cold Spring Harbor Laboratory is a world-renowned biomedical research institution in New York. It has shaped contemporary biomedical research and is the home of eight Nobel Prize laureates. Cold Spring Harbor Laboratory provides a highly dynamic and interactive research environment and also a unique opportunity of timely exposure to advances in various biomedical research fields and of interaction with a broad range of researchers from all over the world through its renowned Meetings and Courses program. We believe that science is for everyone and our researchers have a wide variety of backgrounds.  

Compensation and Benefits
Our employees are compensated in many ways for their contributions to our mission, including competitive pay, exceptional health benefits, retirement plans, time off, and a range of recognition and wellness programs. Visit our CSHL Benefits sites to learn more. The salary range for this role is $45,000-49,449. The salary range and/or hourly rate listed is a good faith determination of potential base compensation that may be offered to a successful applicant for this position at the time of this job advertisement and may be modified in the future. When determining a base salary and/or rate, several factors may be considered as applicable (e.g., years of relevant experience, education, credentials, and internal equity).
 
CSHL is an EO Employer. All qualified applicants will receive consideration for employment and will not be discriminated against on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability or protected veteran status. VEVRAA Federal Contractor

Required: Bachelor's degree or equivalent in molecular biology, biochemistry, cell biology, or related biological discipline.
Preferred: Experience in molecular cloning and mammalian cell culture Familiarity with genetic screens, such as MPRAs. Interest in learning about AI modeling

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About Cold Spring Harbor Laboratory

Since 1890, Cold Spring Harbor Laboratory (CSHL) has been a global leader in research and education. The international scientific community at CSHL provides a unique and stimulating atmosphere for doctoral research?an environment where students, postdoctoral fellows, and faculty work side-by-side. The Watson School of Biological Sciences (WSBS) was founded on the belief that with well thought-out mechanisms, enthusiastic involvement of faculty, and highly motivated students, an innovative curriculum could be provided that would allow students to earn a doctoral degree in a shorter time than in traditional programs without compromising the quality of their training. The curriculum is designed to train students to become scholars and independent thinkers.

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