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Rutgers, The State University of New Jersey is seeking a highly motivated Research Assistant within the Rutgers Cancer Institute.
The Research Assistant will contribute to cutting-edge research in targeted cancer therapeutics and gene therapy. The Research Assistant will work under the guidance of the Principal Investigators to explore the development of phage/AAVP-based therapies, antibody-drug conjugates (ADCs), and novel molecular targets for cancer treatment.
This position is ideal for candidates with a strong interest and a background in molecular biology, bioinformatics, and translational research. The Research Assistant will be involved in independent and collaborative projects, integrating experimental and computational approaches to advance preclinical research.
Among the key duties for this position are the following:
Conducts molecular and cellular biology experiments, including RNA extraction, cDNA synthesis, PCR, and immunoassays.
Performs protein analysis, such as Western blotting, SDS-PAGE, and ELISA, to assess target expression in tumor models.
Executes phage display and AAVP selection experiments for targeted gene therapy applications.
Participates in the design and validation of functional assays for preclinical drug evaluation.
Maintains and analyzes patient-derived xenografts (PDX) and murine cancer models, including tumor monitoring, and ADC efficacy testing.
Works with molecular biology techniques, including DNA manipulation, cloning, and transformation.
Minimum Education and Experience:
Bachelor's Degree in Molecular & Cell Biology or related is required.
Prior laboratory experience in phage display and tumor modeling is required.
Successful candidate will have proficiency in data analysis and scientific software (MATLAB, ImageJ, Prism, Excel).
City: Newark
State: NJ
Physical Demands and Work Environment:
PHYSICALDEMANDS:
Standing, sitting, walking, talking and hearing.
No special vision requirements.
Lifting up to 25 lbs.
WORKENVIRONMENT:
Laboratory work environment, with moderate noise.
Exposure to biological specimens (cells, blood, tissues, etc.) with possible exposure to infectious diseases and hazardous chemicals, including therapeutic drugs.
The laboratory environment operates under mandatory universal safety precautions.
Rutgers, The State University of New Jersey, is a leading national public research university and the state's preeminent, comprehensive public institution of higher education. Rutgers is dedicated to teaching that meets the highest standards of excellence; to conducting research that breaks new ground; and to turning knowledge into solutions for local, national, and global communities. As it was at our founding in 1766, the heart of our mission is preparing students to become productive members of society and good citizens of the world. Rutgers teaches across the full educational spectrum: preschool to precollege; undergraduate to graduate and postdoctoral; and continuing education for professional and personal advancement. Rutgers is New Jersey's land-grant institution and one of the nation's foremost research universities, and as such, we educate, make discoveries, serve as an engine of economic growth, and generate ideas for improving people's lives.