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Position Summary:

• Performs molecular biology, structural biology, X-ray crystallographic, cryo-EM, and genetic research independently or as assigned, relating to bacterial protein structure-function, followed by appropriate reports, recommendations and conclusions.
• Determining the 3-dimensional structures of proteins, protein-protein, and protein-small molecule complexes using X-ray crystallography and cryo-EM,.
• Perform protein expression and purification – overexpression using bacterial systems, SDS-PAGE, western blotting, co-immunoprecipitation, and chromatographic separation using FPLC.
• Perform protein characterization – using circular dichroism, surface plasmon resonance (Biacore), microscale thermophoresis, and isothermal titration calorimetry.
• Perform RNA/DNA isolation, expression vector design and construction, PCR, site-directed mutagenesis, and enzymatic assay development for medium- and high-throughput screening.
• Generates, compiles and presents statistical data with appropriate conclusions, recommendations, etc. pertinent to research activity.
• Support the daily operations within the lab, e.g., lab reagent generation and administrative tasks

Minimum Education and Experience:

• Ph.D. degree in Biochemistry and Structural Biology or equivalent in a relevant science during which a minimum of four (4) years of related research experience was performed.
• Minimum of two years postdoctoral experience.
• Experience with purifying and crystallizing proteins.
• Experience determining X-ray crystal structures and collecting X-ray diffraction data at synchrotrons.

City: Newark

State: NJ

Physical Demands and Work Environment:

• Must be able to safely perform laboratory experiments.
• Laboratory environment.

Salary: 62,326

Posting Number: 23ST0820

About Rutgers University

Rutgers, The State University of New Jersey, is a leading national public research university and the state's preeminent, comprehensive public institution of higher education. Rutgers is dedicated to teaching that meets the highest standards of excellence; to conducting research that breaks new ground; and to turning knowledge into solutions for local, national, and global communities. As it was at our founding in 1766, the heart of our mission is preparing students to become productive members of society and good citizens of the world. Rutgers teaches across the full educational spectrum: preschool to precollege; undergraduate to graduate and postdoctoral; and continuing education for professional and personal advancement. Rutgers is New Jersey's land-grant institution and one of the nation's foremost research universities, and as such, we educate, make discoveries, serve as an engine of economic growth, and generate ideas for improving people's lives.

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