Scheduled Hours

40

Position Summary

The Cruchaga Lab, member of the NeuroGenomics and Informatics Center, (NGI) at Washington University School of Medicine is recruiting a Senior Bioinformatics Scientist. We are seeking an experienced, self-motivated, self-driven scientist to work as a part of vibrant group in a fast-paced environment. The new Senior Bioinformatics Scientist should have wide and solid expertise in WES/WGS, GWAS and/or RNA-seq data analyses to work and lead several projects on the identification of genes dysregulated in Alzheimer disease. They will work in a collegial environment and join a multidisciplinary, diverse team in a well-stablished, well-funded research group, currently 30+ dynamic members, developing bioinformatics and analyzing multi omics data to explore the frontiers of neurodegenerative diseases.
The NGI generates and analyzes Whole-Genome and high-throughput multi-dimensional omics data to study neurodegenerative diseases of the central nervous system with emphasis on Alzheimer's and Parkinson's diseases. The goal of our research is to use genomic and multi-omic approaches to understand the biology of Alzheimer's and Parkinson diseases. Our labs have pioneered the use of new biomarkers as endophenotypes for genetic studies.

Diversity is a core value at Washington University School of Medicine and in the Department of Psychiatry. We are committed to building and sustaining inclusive and equitable working and learning environments for all students, staff, trainees, and faculty. We believe that building a diverse team enriches us individually and as a department by exposing us to a broad range of ways to understand and engage with the world, identify challenges, and to discover, design and deliver solutions. In order to achieve these objectives, candidates are expected to align with the school's mission of promoting inclusive excellence. They should be prepared to further this objective within Washington University and collaborate with diverse communities of students, faculty, staff, trainees, and patients. Visit our Websites to learn more about DEI initiatives in the Department of Psychiatry (https://psychiatry.wustl.edu/diversity-equity-inclusion-2/) and at WUSM (https://diversity.med.wustl.edu/).

Job Description

Primary duties

• Develop a wide variety of computer programs to meet the needs of data collection, quality control, analysis and report generation independently.
• Lead and manage research projects and work together with junior members to complete data processing and analysis following specific timelines.
• Lead complex data analysis and writes interpretative reports for PIâ™s.
• Lead and collaborate within cross-functional teams.
• Lead analytical support for internal projects and external collaborations.
• Supervise database structure: includes updating, validating, curating and harmonizing longitudinal, cross-sectional data from different sources.
• Provide a centralized, confidential and secure access to phenotypic data to Principal investigators.
• Lead the response to data queries from Principal Investigators and external collaborators.
• Create reports and prepare high technical presentations.
• Write manuscripts and communications for conference presentations.
• Present data in meetings and conferences.
• Perform other duties as assigned.

Applicant Special Instructions

Interested candidates please send cover letter and resume to Christi Gleason, Program Manager. cgleason@wustl.edu.

Preferred Qualifications

• Ph.D. degree in Neurogenetics, Bioinformatics, Computational Biology, Statistical Genetics, Biostatistics, Medical Statistics, Neuroscience, Genetics, Statistics, Mathematics or related.
• Six years of experience working in genomics with large datasets, preferably in a research environment.
• Strong background in PLINK, QC, IBD, PCA; R, bash and excel (Python, Perl, SAS, SQL, Docker are a plus) or other analyses toolset.
• Knowledge of association analyses, PRSice, MAGENTA, Mendelian Randomization, MANTRA, Coloc, QTL and Unix/Linux.
• Excellent communication and problem solving skills.
• Familiar working in cross-functional teams.
• Knowledge of neuroscience and neurodegeneration is highly beneficial.
• Good understanding of computational biology and flexibility to work within a large dynamic scientific team.

Required Qualifications

PhD degree in computer science, bioinformatics, biostatistics, or related field, plus six years of experience; or a Master's degree in computer science, bioinformatics, biostatistics, or a related field plus ten years of experience. 

Grade

R13

Salary Range

$72,900.00 - $132,200.00 / Annually

The salary range reflects base salaries paid for positions in a given job grade across the University. Individual rates within the range will be determined by factors including one's qualifications and performance, equity with others in the department, market rates for positions within the same grade and department budget.

Questions

For frequently asked questions about the application process, please refer to our External Applicant FAQ.

Accommodation

If you are unable to use our online application system and would like an accommodation, please email CandidateQuestions@wustl.edu or call the dedicated accommodation inquiry number at 314-935-1149 and leave a voicemail with the nature of your request.

Pre-Employment Screening

All external candidates receiving an offer for employment will be required to submit to pre-employment screening for this position. The screenings will include criminal background check and, as applicable for the position, other background checks, drug screen, an employment and education or licensure/certification verification, physical examination, certain vaccinations and/or governmental registry checks. All offers are contingent upon successful completion of required screening.

Benefits Statement

Personal

• Up to 22 days of vacation, 10 recognized holidays, and sick time.

• Competitive health insurance packages with priority appointments and lower copays/coinsurance.

• Want to Live Near Your Work and/or improve your commute? Take advantage of our free Metro transit U-Pass for eligible employees. We also offer a forgivable home loan of up to $12,500 for closing costs and a down payment for homes in eligible neighborhoods.

• WashU provides eligible employees with a defined contribution (403(b)) Retirement Savings Plan, which combines employee contributions and university contributions starting at 7%.

Wellness

• Wellness challenges, annual health screenings, mental health resources, mindfulness programs and courses, employee assistance program (EAP), financial resources, access to dietitians, and more!

Family

• We offer 4 weeks of caregiver leave to bond with your new child. Family care resources are also available for your continued childcare needs. Need adult care? Weâ™ve got you covered.

• WashU covers the cost of tuition for you and your family, including dependent undergraduate-level college tuition up to 100% at WashU and 40% elsewhere after seven years with us.

For policies, detailed benefits, and eligibility, please visit: https://hr.wustl.edu/benefits/

EEO/AA Statement

Washington University in St. Louis is committed to the principles and practices of equal employment opportunity and especially encourages applications by those from underrepresented groups. It is the Universityâ™s policy to provide equal opportunity and access to persons in all job titles without regard to race, ethnicity, color, national origin, age, religion, sex, sexual orientation, gender identity or expression, disability, protected veteran status, or genetic information.

Diversity Statement

Washington University is dedicated to building a diverse community of individuals who are committed to contributing to an inclusive environment â“ fostering respect for all and welcoming individuals from diverse backgrounds, experiences and perspectives. Individuals with a commitment to these values are encouraged to apply.

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