Dr. Schrauwen at the Center for Statistical Genetics in the Neurology Department is searching for a qualified postdoctoral bioinformatician to aid in a research project focused on the genetic background of neurodevelopmental disorders and other developmental abnormalities. Some of these children endure years-long diagnostic odysseys of trial-and-error testing with inconclusive results and misdirected treatments. The goal of this research is to expand our knowledge on the genetic etiology of these disorders and improve diagnostic testing. The candidate will aid in the analysis of a variety of genetic techniques, including next generation sequencing, long read sequencing, optical genome mapping and epigenomic techniques. We are looking for a talented, passionate, and highly motivated individual to take part in our research mission and to lead the computational efforts in our group.
Duties will include, but will not be limited to:
Create and maintain bioinformatic pipelines on a high-computing cluster
Lead the analysis of novel techniques and novel "omic" data types
Participate in data interpretation such as data quality control, variant interpretation and classification
Utilize good coding practices including versioning (eg. Github) and writing detailed documentation
Participate in manuscript writing and the presentation of results in scientific meetings
Work independently and in a team of scientists
PhD with an emphasis in genetics, bioinformatics, biostatistics, biology, biochemistry, computer sciences or a related field. Experience with linux shell coding, R and Python are a must.
Experience in analyzing next generation sequencing data
Comfortable with job submission on a high-computing cluster
Effective communication, organization and documentation skills
Excellent trouble shooting skills
Columbia University is an Equal Opportunity Employer / Disability / Veteran
Columbia University is one of the world's most important centers of research and at the same time a distinctive and distinguished learning environment for undergraduates and graduate students in many scholarly and professional fields. The University recognizes the importance of its location in New York City and seeks to link its research and teaching to the vast resources of a great metropolis. It seeks to attract a diverse and international faculty and student body, to support research and teaching on global issues, and to create academic relationships with many countries and regions. It expects all areas of the university to advance knowledge and learning at the highest level and to convey the products of its efforts to the world.