Berkeley Lab's Environmental Genomics & Systems Biology (EGSB) Division is looking for a talented Postdoctoral Fellow to join their Microbial Genome Program!
In this exciting role, you will work on single-cell projects and be responsible for the establishment of methodologies that will enable the selective isolation, whole genome amplification, and sequencing of single environmental microbial cells which produce secondary metabolites, in a high throughput manner. The research will focus on the use of fluorescently labeled probes and high throughput probe-based single cell isolation and sequencing approaches. You will perform phylogenetic and functional diversity studies and comparative sequence analysis.
What You Will Do:
Create, design, and execute experiments that will enable the selective isolation and shotgun sequencing of microbial cells of interest.
Work with isolates involved in secondary metabolite production and test new methods.
Perform fluorescence microscopy imaging.
Sample marine invertebrate animals.
Build phylogenetic trees, analyze annotated genomes, and perform comparative genome analysis with a focus on biosynthetic gene clusters.
Apply standard bioinformatics tools for the analysis of large-scale genomic/metagenomic data.
Publish in peer review journals and deliver scientific presentations at scientific meetings.
What is Required:
A recent PhD in Molecular Biology, Microbiology, Biochemistry, Genetics, or a related discipline with an emphasis in Bioinformatics within the last 2 years.
Experience with fluorescently labeled probes and fluorescent-activated cell sorting.
Knowledge of molecular biology techniques such as PCR, qPCR, cloning, whole genome amplification.
Knowledge in microbial ecology, physiology, biochemistry, biogeochemistry, molecular biology and understanding of key and complex biological concepts (genes, pathways, microbial phylogeny).
Familiarity with secondary metabolites in bacteria and the microbiomes of marine invertebrates.
with a proven track record in this area reflected in recent or pending publications.
Experience with UNIX utilities and filesystems, R statistical analysis platform, and standard bioinformatics tools and databases.
Excellent oral and written communication skills including the ability to organize/present technical reports and provide a proven track record of recent or pending scientific publications.
Demonstrated interpersonal skills including experience collaborating with a diverse interdisciplinary research team.
What We Prefer:
Experience in any of the following areas: single cell genomics, microbial genomics, metagenomics, including data processing/ analysis.
Experience with next generation sequencing platforms (Illumina, PacBio, ONT).
Familiarity with command line sequence analysis tools (e.g., Last, Hmmer, Megahit, MetaSpades, etc.).
For full consideration, please apply with the following application materials:
Cover Letter - Describe your interest in this position and the relevance of your background.
Curriculum Vitae (CV) or Resume.
This is a full time, exempt from overtime pay (monthly paid), 3 year appointment with the possibility of renewal based upon satisfactory job performance, continuing availability of funds, and ongoing operational needs. You must have less than 2 years of paid postdoctoral experience.
This position is represented by a union for collective bargaining purposes with predetermined postdoctoral step rates dependent on years of experience post-degree.
Salary is commensurate with experience.
This position may be subject to a background check. Any convictions will be evaluated to determine if they directly relate to the responsibilities and requirements of the position. Having a conviction history will not automatically disqualify an applicant from being considered for employment.
Work will be performed onsite at Lawrence Berkeley National Lab, 1 Cyclotron Road, Berkeley, CA.
Learn About Us:
Berkeley Lab (LBNL) addresses the world's most urgent scientific challenges by advancing sustainable energy, protecting human health, creating new materials, and revealing the origin and fate of the universe. Founded in 1931, Berkeley Lab's scientific expertise has been recognized with 13 Nobel prizes. The University of California manages Berkeley Lab for the U.S. Department of Energy's Office of Science.
Berkeley Lab's Postdoc Program is committed to providing Postdoctoral Researchers and Visiting scholars with a positive and impactful experience to jump-start their career through premium research and career development, networking opportunities, mentoring programs, and a strong community. For more information, please visit our Berkeley Lab Postdoc Resources site and our Berkeley Lab Postdoc Association site.
Based on University of California Policy - SARS-CoV-2 (COVID-19) Vaccination Program and U.S Federal Government requirements, Berkeley Lab requires that all members of our community obtain the COVID-19 vaccine as soon as they are eligible. As a condition of employment at Berkeley Lab, all Covered Individuals must Participate in the COVID-19 Vaccination Program by providing proof of Full Vaccination or submitting a request for Exception or Deferral. Visit covid.lbl.gov for more information.
Berkeley Lab is an Equal Opportunity and Affirmative Action Employer. We heartily welcome applications from women, minorities, veterans, and all who would contribute to the Lab's mission of leading scientific discovery, inclusion, and professionalism. In support of our diverse global community, all qualified applicants will be considered for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age, or protected veteran status.
In the world of science, Lawrence Berkeley National Laboratory (Berkeley Lab) is synonymous with excellence. Thirteen scientists associated with Berkeley Lab have won the Nobel Prize. Fifty-seven Lab scientists are members of the National Academy of Sciences (NAS), one of the highest honors for a scientist in the United States. Thirteen of our scientists have won the National Medal of Science, our nation's highest award for lifetime achievement in fields of scientific research. Eighteen of our engineers have been elected to the National Academy of Engineering, and three of our scientists have been elected into the Institute of Medicine. In addition, Berkeley Lab has trained thousands of university science and engineering students who are advancing technological innovations across the nation and around the world. Berkeley Lab is a member of the national laboratory system supported by the U.S. Department of Energy through its Office of Science. It is managed by the University of California (UC) and is charged with conducting unclassified research across a wide range of scientific disciplines. Located on a 200-acre site in the hills above the UC Berkeley campus that offers spectacular... views of the San Francisco Bay, Berkeley Lab employs approximately 4,200 scientists, engineers, support staff and students. Its budget for 2011 is $735 million, with an additional $101 million in funding from the American Recovery and Reinvestment Act, for a total of $836 million. A recent study estimates the Laboratory's overall economic impact through direct, indirect and induced spending on the nine counties that make up the San Francisco Bay Area to be nearly $700 million annually. The Lab was also responsible for creating 5,600 jobs locally and 12,000 nationally. The overall economic impact on the national economy is estimated at $1.6 billion a year. Technologies developed at Berkeley Lab have generated billions of dollars in revenues, and thousands of jobs. Savings as a result of Berkeley Lab developments in lighting and windows, and other energy-efficient technologies, have also been in the billions of dollars. Berkeley Lab was founded in 1931 by Ernest Orlando Lawrence, a UC Berkeley physicist who won the 1939 Nobel Prize in physics for his invention of the cyclotron, a circular particle accelerator that opened the door to high-energy physics. It was Lawrence's belief that scientific research is best done through teams of individuals with different fields of expertise, working together. His teamwork concept is a Berkeley Lab legacy that continues today.