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American Society of Human Genetics
Rockville, Maryland
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Cincinnati, Ohio
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Cambridge, Massachusetts
Yale University School of Medicine
New Haven, Connecticut
Institute for Genomic Health at the Icahn School of Medicine at Mount Sinai
New York, New York
Assistant or Associate Professor in the Institute for Genomic Health and the Division of Genomic Med
Mount Sinai Institute for Genomic Health
New York, New York
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Research Opportunities (Mechanistic Cancer Research) - Molecular Oncology
Scheduled Hours40Position SummaryJob DescriptionCancer is a heterogeneous disease driven by various genomic, epigenomic, and proteomic abnormalities. Though conceptually straightforward, targeting cancer-specific abnormalities proves practically challenging due to the complexity of the cellular functions of many potential cancer targets. The main interest of the lab is unravelling the biology of cancer-relevant cellular proteins with poorly understood mechanisms with the overarching goal of developing novel and more effective therapies. Currently, we are focusing on two multifunctional proteins, the actin-binding protein Profilin-1 and the AAA+ ATPase p97/VCP. Both are essential proteins with well-known functions
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