The Keck School of Medicine, department of Pathology is seeking to hire a Postdoctoral position for a highly motivated fellow to explore tissue patterning in development and regeneration.Project: Channel activity and epigenetic control in skin tissue pattern formation.To study roles of channel activities in tissue morphogenesis and pattern formation, we use developing chicken skin and a regenerating feather follicle model. A combination of next-gen sequencing, molecular expression, lentivirus-mediated gene misexpression, 4D cell behavior movies, and electro-physiology will be used to identify roles of ion channels and gap junctions in morphogenesis. We also pursue how gap junction activity may modify epigenetic regulation to control skin appendage phenotypes.
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