The postdoctoral position will be part of a team effort to investigate HIV-induced vascular dysfunction and neuroAIDS molecular mechanisms using in vitro and in vivo (animal models) approaches. Specifically, the person will utilize HIV mouse models and HIV-1 infected cellular models to conduct experiments investigating the molecular events associated with cellular and vascular dysfunction in neuroAIDS. These studies will involve advanced molecular biology, including single cell transcriptomics, genomics and epigenomics, data analysis and interpretation. Additionally, molecular and cell biology techniques include molecular cloning, gene transfection and expression, siRNA technology, qPCR, FACS analysis, confocal imaging, histology, immunohistochemistry, immunofluorescence, ELISA, Western blots, and other protein chemistry techniques. The ideal candidate will be creative, highly motivated and have significant experience in these molecular and cell biology techniques; and preferably experience working with laboratory animals, including animal injection, collection and processing of animal tissues and biological fluids; and analyses of these samples. The candidate should be able to design and perform experiments with minimal supervision, critically analyze the results, summarize, present, and discuss the results with other team members, and help write manuscripts for publications.

PhD

Ability to perform in vivo experiments with mice (including drug treatment/injection, blood collection, tissue harvesting, downstream analyses of blood and tissues); experience in molecular biology, single cell transcriptomics, genomics and/or epigenomics analyses.