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The laboratory of Dr. Yankner at Harvard Medical School is seeking a highly motivated Postdoctoral Fellow to investigate the molecular genetics and neurobiology underlying microglial and oligodendrocyte function in the context of aging, neurodegeneration, and Alzheimer's disease. The successful candidate will join a dynamic and collaborative research environment focused on uncovering the cellular and molecular mechanisms driving cognitive decline and neurodegenerative processes.
Responsibilities: Conduct biochemical, genetic, and transcriptomic analyses of key regulators of brain aging using mouse and cerebral organoid models. Design and perform experiments to study the roles of microglia and oligodendrocytes in neurodegeneration and cognitive function. Analyze high-dimensional data to identify molecular pathways and targets relevant to Alzheimer's disease and age-related decline. Collaborate with lab members and external researchers to advance shared projects and publications. Contribute to the preparation of manuscripts, grant proposals, and presentations. Mentor junior researchers and assist in training lab members in experimental techniques and data analysis.
Basic Qualifications:
Ph.D. or M.D./Ph.D. in areas such as neuroscience, molecular biology, genetics, bioinformatics, or a related field.Strong background in neurobiology, systems biology, or neurodegenerative disease models.
Prior experience with transcriptomic or molecular analyses in cell culture or animal model systems.
Contact Information:
Genetics Hire Team
Contact Email: Yachao_Wang@hms.harvard.edu
Special Instructions:
Required documents:
Curriculum Vitae
Statement of Research for PhD work
Cover Letter describing your interest in the lab and initial ideas for new research directions or projects you could undertake in the lab.
Note with names and contact information for three people who have agreed to serve as your reference
Please submit application documents through the ARIeS portal. Applications will be considered. Selected candidates will be invited for in-person interviews involving a research presentation on past work.
Expected Dates
Application deadline: 11/24/2025
Start date: The position is expected to start on or around 1/2/2026 with some flexibility.
Duration: This is a one-year term position from the date of hire, with the possibility of extension, contingent upon work performance, business need, and continued funding to support the position.
Equal Opportunity Employer:
Harvard has an equal employment opportunity policy that outlines our commitment to prohibiting discrimination on the basis of race, sex, ethnicity, color, national origin, religion, disability, or any other characteristic protected by law or identified in the university's non-discrimination policy.
Harvard University is devoted to excellence in teaching, learning, and research, and to developing leaders in many disciplines who make a difference globally. The University, which is based in Cambridge and Boston, Massachusetts, has an enrollment of over 20,000 degree candidates, including undergraduate, graduate, and professional students. Harvard has more than 360,000 alumni around the world. The University has twelve degree-granting Schools in addition to the Radcliffe Institute for Advanced Study, offering a truly global education. Established in 1636, Harvard is the oldest institution of higher education in the United States.