How are yeast metabolic functions genetically encoded? How did they evolve? How can they be manipulated for sustainable human benefit?  DNA sequencing and synthesis allow us to read and write from genomes at a breathtaking pace, and yeasts are leading the way. Yeasts of the subphylum containing S. cerevisiae, C. albicans, St. bombicola, and Y. lipolytica are as genetically diverse as the animal kingdom and have evolved myriad energy management strategies to process carbon. Yeasts compete vigorously for nutrients in every continent and biome, but most species are minimally characterized. You can be among the first to study yeast evolution, ecology, or bioenergy applications using data from Y1000+ Project (