Organization OverviewRNA is the driving force of biological complexity,determining which genes any given cell expresses at specific times and under specific circumstances. Darnell developed high-throughput sequencing and crosslinking methods to investigate how RNA binding proteins (RBPs) modulate gene expression. He discovered neuron-specific RNA-binding proteins in the mammalian brain,and studies their link to intellectual function and human disease. OverviewThe Laboratory of Molecular Neuro-oncology focuses on characterizing the molecular mechanisms that underlie pain and inflammation in patients with arthritis.  Current efforts are focused on understanding neuroimmune interactio