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Research Scientist, Department of Cancer Biology, College of Medicine
University of Cincinnati
Application
Details
Posted: 13-May-25
Location: Cincinnati, Ohio
Internal Number: 98991-en_US
Current UC employees must apply internally via SuccessFactors
Founded in 1819, the University of Cincinnati ranks among the nation?s best urban public research universities. Home to 53,235 students, nearly 12,000 faculty and staff and 350,000+ living alumni, UC combines a Top 35 public research university with a physical setting The New York Times has called ?the most ambitious campus design program in the country.?
With the launch of Next Lives Here, the Cincinnati Innovation District, a $100 million JobsOhio investment, the oldest and one of the largest cooperative education programs, a dynamic academic health center and entry into the Big 12 Conference, UC?s momentum has never been stronger. UC?s annual budget stands at $1.85 billion, and its endowment totals $2 billion.
UC is a mission-driven organization where we are committed to student success and positively transforming the community through scholarship and service. We thrive on innovation, making an impact, and fostering an environment where staff and faculty are key contributors to UC?s success.
Job Overview
A Research Scientist position is available in the laboratory of Dr. Xiaoting Zhang in the Department of Cancer Biology at the University of Cincinnati College of Medicine, to study transcriptional and epigenetic gene regulation in breast cancer metastasis and therapeutic resistance. The Zhang laboratory (https://med.uc.edu/zhanglab) currently focuses on elucidating the role and molecular mechanisms of gene- and tissue-specific transcriptional cofactors, small RNAs and liquid-liquid phase separation (LLPS) in the above processes [Estrogen Receptor and Breast Cancer ? Celebrating the 60th Anniversary of the Discovery of ER (1st ed, 2019, Springer Nature), Dev Cell (2021)56(3):341, Cell Reports (2021) 34(10):108822, Cancer Drug Resist 2022; 5(2): 498, Autophagy (2023) 19(6):1662, Cancers (2024) 16(23):3992]. We are using a combination of biochemical, molecular, genomic, and mouse genetic (conditional knockout, mutant knockin, and overexpression) approaches. We are also currently developing RNA-based nano-therapeutics to target these cofactors and small RNAs to overcome the therapeutic resistance of human breast cancer.
Essential Functions
Independently design and conduct the research required by the faculty supervisor to a high standard and in accordance with all institutional and federal regulations.
Prepare research results, write manuscripts independently, and engage in the dissemination and presentation of the results of the research.
Support the development of proposals and write research-related funding and grants.
Partaking in appropriate training and professional development opportunities.
May provide direct and/or indirect supervision to exempt and non-exempt staff and perform additional related duties as needed.
Required Education
PhD and/or MD required.
Required Experience
Additional related work experience may be required depending on field or discipline.
Additional Qualifications Considered
Prior experience and in-depth knowledge in cancer biology, molecular cellular biology, protein biochemistry, small RNAs, or LLPS is ideal.
Physical Requirements/Work Environment
Sitting - Continuously
Repetitive hand motion (such as typing) - Often
Hearing, listening - Often
Talking - Often
Standing - Often
Walking - Often
Bending - Seldom
Stooping - Seldom
Climbing stairs/ladders - Seldom
Kneeling, squatting - Seldom
Crouching - Seldom
Crawling - Seldom
Reaching overhead - Seldom
Lifting - up to 20 pounds - Seldom
Lifting - up to 50 pounds - Seldom
Lifting - over 50 pounds - Seldom
Compensation and Benefits
UC offers an exceptional benefits package designed to support your well-being, financial security, and work-life balance. (UC Benefits Link) Highlights include:
Comprehensive Tuition Remission
UC provides tuition remission for you and your eligible dependents, covering tuition costs for nearly all undergraduate and graduate programs offered by the university.
Robust Retirement Plans
As a UC employee, you won?t contribute to Social Security (except Medicare). Instead, you?ll choose between state pension plans (OPERS, STRS) or an Alternative Retirement Plan (ARP), with UC contributing 14?18% of your salary based on position.
Real Work-Life Balance
UC prioritizes work-life balance with a generous time-off policy, including:
Vacation and sick time
11 paid holidays and additional end-of-year paid time off (Winter Season Days)
6 weeks of paid parental leave for new parents
Additional Benefits Include:
Competitive salary based on experience
Comprehensive health coverage (medical, dental, vision, prescription)
Flexible spending accounts & wellness programs
Professional development & mentorship opportunities
UC is an E-Verify employer. If hired into this position, you will be required to provide satisfactory proof of employment eligibility by providing acceptable, original forms of identification for employment verification via the Federal I-9 employment verification process. A list of acceptable documents can be seen here: https://www.uscis.gov/i-9-central/form-i-9-acceptable-documents
Important: To apply you must create a profile and submit a complete job application through the UC applicant portal. We are unable to consider ?easy apply? applications submitted via other websites. For questions about the UC recruiting process or to request accommodations with the application, please contact Human Resources at jobs@uc.edu.
The University of Cincinnati is an Equal Opportunity Employer.
HISTORY IN BRIEF - The University of Cincinnati is a public urban serving research institution that was founded in 1819 and today is one of the country’s largest universities offering more than 350 academic programs to more than 44,000 students. UC has many top ranked programs in areas such as Music and Arts, Medical and Human-Services, Criminal Justice and more. Located in an urban setting, UC is close to the heart of Cincinnati and allows easy access for students to enjoy all that the city offers. UC is also the alma mater of many notables such as President William Howard Taft; Albert Sabin, developer of the oral polio vaccine; Astronaut Neil Armstrong and Mary Weinberg, 2008 Olympic gold medalist. UC is classified as a Research University (Very High Research Activity) by the Carnegie Commission and is ranked as one of America’s top 35 public research universities by the National Science Foundation. UC jumped 17 spots in the U.S. News & World Report rankings in the past two years alone. In addition to being named a “green university” by Princeton Review, UC has been named one of the world’s most beautiful campuses by Forbes and Delta Sky magazines. Learn more at www.uc.edu.MISSIO...N STATEMENT - The University of Cincinnati serves the people of Ohio, the nation, and the world as a premier, public, urban research university dedicated to undergraduate, graduate, and professional education, experience-based learning, and research. We are committed to excellence and diversity in our students, faculty, staff, and all of our activities. We provide an inclusive environment where innovation and freedom of intellectual inquiry flourish. Through scholarship, service, partnerships, and leadership, we create opportunity, develop educated and engaged citizens, enhance the economy and enrich our University, city, state and global community.