A cover letter is required for consideration for this position and should be attached as the first page of your resume. The cover letter should address your specific interest in the position and outline skills and experience that directly relate to this position.

The lab of Zhong Wang, PhD housed within the Department of Cardiac Surgery is seeking a self-motivated and career-oriented postdoctoral research fellow to join an exciting and highly interactive research team. This position will conduct research with a goal of developing heart therapies to effectively prolong and improve the life of patients with cardiovascular disease.

The position will be focused on epigenetic regulation in heart disease, heart repair, and heart regeneration with three major research directions:

1. Define essential cross-talks between histone acetylation and acetyl-CoA mediated energy metabolism in heart repair and regeneration.
2. Identify epigenetic and post-translational modification mechanism and related molecules in stimulating reprogramming of fibroblasts into cardiomyocytes for heart regeneration.
3. Explore novel strategies combining optimal cardiovascular cell types and bioengineering/biomaterials for heart cell therapy. 

• Operates with considerable actions or decisions. Responsible for decision making regarding reproductive research and daily activities. May function as liaison with other departments, divisions, or organizations.
• Develops, designs, and conducts one or more large complex research experiments in line with plan, reviews progress and evaluates results.
• Formulates research methods and suggests options for improving quality, identifies potential problems, recommends, and implements solutions.
• Trains users in equipment operations and laboratory techniques. May also mentor students in the lab.
• Consults with users to refine or adapt methodologies to fit specific experimental requirements.
• Works directly with PI on the development and implementation of research plans and goals.
• Co-authors publications and manuscripts. 
• Presents research findings.

• PhD degree in biochemistry/cell and molecular biology/biomedicine.
• Strong background in biochemistry, cell biology, stem cells, and related fields accompanied by a proven track record of publications.
• Specialized expertise in stem cell culture and animal work, and a demonstrated history of successful engagement in such experiments are particularly preferred.
• Proficiency in protein-protein interactions, CRISPR/Cas9 gene editing, RNA-seq, flow cytometry, immunostaining, PCR, Western blot, animal experiments, mouse reproduction, DNA transformation, and molecular biology is highly desirable.

Michigan Medicine conducts background screening and pre-employment drug testing on job candidates upon acceptance of a contingent job offer and may use a third party administrator to conduct background screenings.  Background screenings are performed in compliance with the Fair Credit Report Act. Pre-employment drug testing applies to all selected candidates, including new or additional faculty and staff appointments, as well as transfers from other U-M campuses.

Michigan Medicine improves the health of patients, populations and communities through excellence in education, patient care, community service, research and technology development, and through leadership activities in Michigan, nationally and internationally. Our mission is guided by our Strategic Principles and has three critical components; patient care, education and research that together enhance our contribution to society.

Job openings are posted for a minimum of seven calendar days.  The review and selection process may begin as early as the eighth day after posting. This opening may be removed from posting boards and filled anytime after the minimum posting period has ended.

The University of Michigan is an equal employment opportunity employer.

About University of Michigan - Ann Arbor

A great university is made so by its faculty and staff, and Michigan is recognized as one of the best universities to work for in the country. The Michigan culture is known for engaging faculty and staff in all facets of the university to create a workplace that is vibrant and stimulating.For two consecutive years, the Chronicle of Higher Education has placed U-M in its "Great Colleges to Work For" survey. In particular, the university earns high marks for strong relations between faculty and administrators, a collaborative system of governance, strong pay and benefits, and a healthy work/life balance.

Connections working at University of Michigan - Ann Arbor