Research Assistant I - Manis Lab in Boston, MA for Boston Children's Hospital

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Research Assistant I - Manis Lab

The Manis Lab is exploring ways to collect and genetically correct hematopoietic stem cells from patients with sickle cell disease. Studies have demonstrated the success of gene therapy as a therapeutic option with recent FDA approval of two of these products. Some of our areas of study focus on:Optimizing mobilization and HSC collection in sickle cell patients undergoing gene therapyUnderstanding how the bone marrow and hematopoietic cells is altered in SCDUsing mouse modes of SCD to test and visualize the bone marrow and other hematopoietic organsThis role would focus on translational work, characterizing mouse and human stem cells with the opportunity to interact with clinical trial st

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