Postdoctoral Fellow â“ Chemical & Structural Biology and Signal Transduction

Job Description

Saint Louis University is a Catholic Jesuit Institution dedicated to student learning, research, health care, and service. This Postdoctoral Fellow position is in the chemistry research group led by Dr. Ajith Karunarathne in the Department of Chemistry (www.ajithlab.org). This work involves protein engineering and developing the cryo-EM-based structural biology arm of the lab, expanding molecular pharmacology and drug discovery research, assisting with the training of graduate and undergraduate student researchers, and laboratory management.

Responsibilities:

1. Structure-guided engineering and optimization of novel proteins

2. Extensive characterization of proteins both in vitro and in vivo, including Cryo-EM

3. The use of advanced molecular tool to ex-vivo engineering cells (CRISPR)

4. In vivo testing of optogenetics tools

5. Development of virus-based gene delivery methods

6. Mentoring Graduate and Undergraduate Students

Required qualifications:

PhD in Chemistry, structural biology, chemical biology, or a related field

Preferred qualifications:

· Ph.D. in Biochemistry and molecular-cell biology with a focus on protein engineering and signal transduction.

· Significant experience in advanced molecular cloning, protein biochemistry, and single-cell approaches.

· Experience in structural biology, proteomics-lipidomics, and bioinformatics is preferred.

Salary: Commensurate with experience

**Optional** How to apply: Interested applicants should send (1) a cover letter or personal statement

detailing previous/current research experience (1-2 pages), (2) a resume/CV, and (3) three

professional references to Dr. Ajith Karunarathne at wkarunarathne@slu.edu

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About Saint Louis University

Saint Louis University(SLU) is a private, co-educational Jesuit university located in St. Louis, Missouri, United States. Founded in 1818 by the Most Reverend Louis Guillaume Valentin Dubourg SLU is the oldest university west of the Mississippi River. The University has campuses in St. Louis, Mo. and Madrid, Spain. SLU values academic excellence, life-changing research, compassionate health care, and a strong commitment to faith and service. For nearly 200 years, the University has gone beyond teaching facts and figures, encouraging students to form ideas and identities. Today, SLU students are nearly 14,000 strong. The University has invested vast resources to advance academic programs and enhance the student experience. SLU also is a major research institution where premier researchers tackle local and global challenges. And the University's commitment to community service has earned it national acclaim and bolstered its status as a character-building college.

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