The Cell Death Signaling Lab at New York University Abu Dhabi invites applications for a Research Scientist role focused on understanding ferroptosis's role and mechanisms in cellular metabolism, tumor suppression, and cancer therapy through in vitro and in vivo models. This research seeks to clarify how the tumor suppressor protein Par-4 influences NCOA4-mediated ferritinophagy, crucial for providing iron essential for lipid oxidation during ferroptosis. The chosen candidate will spearhead groundbreaking research into the interplay between Par-4 and ferroptosis signaling pathways, contributing to a complex regulatory network with considerable implications for therapy and disease management. A strong background in cancer biology, cellular and molecular signaling, alongside excellent problem-solving and communication skills for presenting and publishing findings, is essential for the ideal candidate

Responsibilities of the position include:

• Design and conduct experiments to identify and explore the biochemical features, morphological features, and regulatory pathways of ferroptosis, apoptosis, necroptosis, autophagy, oxeiptosis, and pyroptosis.
• Plan and conduct experiments to develop new products and processes for studying genes, proteins, and transcription factors involved in ferroptosis.
• Conduct experiments using techniques such as mammalian cell culture, gene expression analysis (RNA-seq), qRT-PCR, cytotoxic assays, Western blotting, DNA and RNA isolation, fluorescent microscopy, FACS, and transient-stable transfection.
• Analyze and interpret results from these techniques using GraphPad Prism, and then publish the results in relevant journals.
• Manage laboratory equipment and materials and keep licensing and certification up to date.
• Collaborate with a multidisciplinary team of PhD scientists, graduate students, and undergraduates, contributing to a dynamic and collaborative research environment.

Candidates must hold a a Ph.D. in Biochemistry or Biotechnology, with a focus in Cancer Biology, Molecular Biology, or a similar area of cancer research. The ideal candidate should have a minimum of ten years of research experience using both qualitative and quantitative methods, specifically related to various cell-death programs, including apoptosis, autophagy, and ferroptosis, and experience in designing and executing experiments with methods like mammalian cell culture, gene expression analysis (RNA-seq), qRT-PCR, cytotoxic assays, Western blotting, DNA and RNA isolation, fluorescent microscopy, FACS, and transient-stable transfection is required.

It would be preferred if the candidate possesses robust analytical skills along with experience in data interpretation, utilizing tools like GraphPad Prism and EndNote for reference management, and hsd a proven publication track record, experience in writing grants and articles, and the capacity to work both independently and collaboratively within a team.

Applications will be accepted immediately and candidates will be considered until the position is filled. To be considered, all applicants must submit a cover letter, curriculum vitae, transcript of degree, research statement, and at least 2 letters of recommendation, all in PDF format. If you have any questions, please email Dr. Galadari: Shg3@nyu.edu

About NYUAD:

NYU Abu Dhabi is a degree-granting research university with a fully integrated liberal arts and science undergraduate program in the Arts, Sciences, Social Sciences, Humanities, and Engineering. NYU Abu Dhabi, NYU New York, and NYU Shanghai, form the backbone of NYU?s global network university, an interconnected network of portal campuses and academic centers across six continents that enable seamless international mobility of students and faculty in their pursuit of academic and scholarly activity. This global university represents a transformative shift in higher education, one in which the intellectual and creative endeavors of academia are shaped and examined through an international and multicultural perspective. As a major intellectual hub at the crossroads of the Arab world, NYUAD serves as a center for scholarly thought, advanced research, knowledge creation, and sharing, through its academic, research, and creative activities.

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UAE Nationals are encouraged to apply.

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