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Polygenic Risk Score development for chronic low back pain
Professors Carolina Meloto and Audrey Grant are hiring one PhD student at the Faculty of Dental Medicine and Oral Health Sciencesat McGill University. This research opportunity is focused on applied approaches directed towards prevention of chronic low back pain (cLBP) development. Broadly, chronic pain is defined based on the persistence of pain experience for over three months and represents a substantial public health burden with a prevalence of 20 % in the general population, with cLBP as the most common chronic pain condition. Accurately predicting individuals who are at risk of cLBP is a vital step needed to enable cLBP prevention strategies. Despite cLBP having a sizable genetic heritability, models proposed to predict cLBP development are based on biopsychosocial measures and do
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