General DescriptionThe O'Brien Lab in the Department of Biophysics and Biophysical Chemistry at the Johns Hopkins University School of Medicine recently opened in August of 2024, and seeks a postdoctoral fellow interested in the discovery and mechanistic characterization of new G-protein coupled receptor (GPCR) ligands as drug leads with a variety of cutting-edge technologies. This work will involve membrane protein biochemistry, selection methodologies, structural biology (cryo-EM), and protein dynamics techniques. This work will be extremely multidisciplinary and involve collaboration across many areas of the drug discovery pipeline, with expertise gained in nearly all areas of early drug discovery. The target start date is negotiable.