Dr. Winson Ho Lab in the Department of Neurosurgery and Brain Tumor Center at University of California, San Francisco are seeking applications for a Junior Specialist. Our lab is focused on identifying the molecular mechanisms driving immunosuppression and evasion in brain tumor microenvironment, such as the biology of tumor associated macrophage and microglia. The candidate will apply cutting-edge approaches in caner immunology research to develop immunotherapy for brain tumor. The selected candidate will contribute to a team in the performance of laboratory and investigative procedures by conducting a variety of experimental techniques such as immunology-based assays, molecular cloning, cell culture (cell lines and primary cells), qPCR, WB, flow cytometry and animal work. The successful candidate should be able to learn new cell biological assays quickly and execute them. Data will need to be collected, verified, recorded, and compiled in support of research.

Essential Duties and Responsibilities:

1. Performing various investigative procedures and operating a variety of instruments and other scientific equipment after training. Examples of equipment routinely used are flow cytometry machine, FACS sorter, qPCR machine.

2. Immune and cancer cell-based co-culture assays.

3. CRISPR gene modification technology for immune and cancer cell lines. Lentivirus and retrovirus plasmids design and virus transduction.

4. Animal work in vivo studies such as intracranial injection, mice breeding colony maintenance, isolate brain tumor tissue for further analysis.

5. Collect, record, organize and verify the accuracy of data; perform calculations and prepare charts, graphs and reports. May use software applications to assemble, manipulate and/or format data and test reports.

Required Qualifications:

• B.S. or B.A. degree in Immunology, Molecular Biology, Biochemistry, or related field by the time of hire.
• Ability to learn new technology quickly.
• Ability to communicate verbally well.
• Ability to draft routine reports and keep accurate records of work performed.
• Actively seeks opportunities to increase skills and expertise.
• Able to learn complex tasks with general instruction.
• Applicants' materials must list current and/or pending qualifications upon submission.

Preferred Qualifications:

• Knowledge of Immunology and bioinformatics is preferable.

See Table 24B for the salary range for this position. A reasonable estimate for this position is $53,100 - $56,600.

Please apply online at https://aprecruit.ucsf.edu/JPF05031.

As a University employee, you will be required to comply with all applicable University policies and/or collective bargaining agreements, as may be amended from time to time. Federal, state, or local government directives may impose additional requirements.

UC San Francisco seeks candidates whose experience, teaching, research, or community service has prepared them to contribute to our commitment to diversity and excellence. The University of California is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age or protected veteran status.

As a condition of employment, the finalist will be required to disclose if they are subject to any final administrative or judicial decisions within the last seven years determining that they committed any misconduct, are currently being investigated for misconduct, left a position during an investigation for alleged misconduct, or have filed an appeal with a previous employer.
* "Misconduct" means any violation of the policies or laws governing conduct at the applicant's previous place of employment, including, but not limited to, violations of policies or laws prohibiting sexual harassment, sexual assault, or other forms of harassment, discrimination, dishonesty, or unethical conduct, as defined by the employer.
* UC Sexual Violence and Sexual Harassment Policy: https://policy.ucop.edu/doc/4000385/SVSH
* UC Anti-Discrimination Policy for Employees, Students and Third Parties: https://policy.ucop.edu/doc/1001004/Anti-Discrimination
* APM - 035: Affirmative Action and Nondiscrimination in Employment: https://www.ucop.edu/academic-personnel-programs/_files/apm/apm-035.pdf