About the Junge Lab: The Junge lab at the University of Minnesota Medical School (Twin Cities) is seeking a talented postdoctoral trainee with aspirations to become an independent scientist in academia or industry. We offer a personalized training plan tailored to your career goals. Our research focuses on neurovascular signaling, utilizing mouse genetics, molecular and protein-biochemical methods, cell biology, and various -omics methods. Currently, we are exploring pharmacological activation of Wnt and Norrin signaling to restore pericytes in the brain and retina. For more information, visit our lab webpage at https://med.umn.edu/ophthalmology/research/junge-lab

Responsibilities:

Experimental Research:

• Conduct in vitro and in vivo experiments focusing on angiogenesis, blood-brain barrier, and neurovascular signaling, utilizing mouse genetic approaches, imaging techniques, and transcriptomics.
• Independently design, execute, and troubleshoot experiments from start to finish, optimizing methods as necessary.
• Propose alternative methods, modify existing procedures, or develop new protocols to achieve research objectives.
• Quickly learn and apply new techniques to advance project goals.
• Analyze, interpret, and present complex experimental data, including performing statistical analyses.

Project Management:

• Fully comprehend project scope and data, driving projects to successful completion.
• Stay updated on technological and scientific advancements in the field.
• Utilize a variety of information resources beyond primary literature, such as public gene expression databases and genetically engineered animal models.
• Understand biological process models, derive predictions, and design/conduct experiments to test these predictions.

Collaboration and Communication:

• Serve as an expert resource for lab members, external collaborators, and the broader scientific community.
• Interact, communicate, and coordinate with various stakeholders, including UMN cores and collaborators, to complete research projects.

Training and Mentorship:

• Assist in training undergraduate and graduate students, providing guidance and support in experimental techniques and research methodologies.

Documentation and Compliance:

• Prepare manuscripts and figures for publication, contributing to the dissemination of research findings.
• Write or modify IACUC protocols.
• Assist with laboratory organization and ensure adherence to all regulatory requirements.

Required Qualifications:

• Advanced degree in Biological Sciences or a related field, with one (1) or more years of related research training.

Preferred Qualifications:

• PhD in Biological Sciences field is highly desired. 
• Prior publications and in-depth knowledge in one or more of the following areas: Vascular Biology, Neuroscience, Ophthalmology, Mammalian Developmental Biology, Cell Biology, Signal Transduction, Extracellular Matrix Biology.
• Hands-on experience with mouse models.
• Strong ability to conceptualize and design scientific projects.
• Excellent communication skills to discuss scientific concepts clearly, concisely, and logically.
• Demonstrated ability to conduct experiments independently, troubleshoot complex technical challenges, and drive scientific projects to successful completion with minimal supervision.

About University of Minnesota Twin Cities

The University of Minnesota, founded in the belief that all people are enriched by understanding, is dedicated to the advancement of learning and the search for truth; to the sharing of this knowledge through education for a diverse community; and to the application of this knowledge to benefit the people of the state, the nation, and the world.

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