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Research Laboratory Tech Assoc. / Interm. (term-limited)
Carry out functional analyses in cell lines and integrating this information with human genetic and phenotype data to elucidate the mechanisms underlying human obesity and fatty liver disease.Essential job duties:25% - Utilize the CRISPR-Cas9 system to knockout genes in a human cell lines in order to elucidate the mechanisms responsible for the development of obesity and fatty liver disease. 25% - Develop and optimize biochemical assays and high-throughput imaging methods to study the precise biological pathways behind particular gene cell phenotypes. 25% - Modify and test guide RNA design in order to maximize efficiency of proper knock
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