Uses skills as a seasoned, experienced research professional with a full understanding of in-depth statistical analyses and / or research software programming techniques. Demonstrates good judgment in selecting methods and techniques for obtaining solutions.Involves technical expertise for planning and performing correlative analyses of biomarker and clinical data from the endocrine optimization pilot EOP I-SPY 2 sub-study trial, as well as the I-SPY suite of trials.Specifically, the EOP I-SPY 2 sub-study trial evaluates the feasibility of neoadjuvant endocrine therapy +/- novel agents in molecularly low risk (but clinically high risk) HR+HER2- patients who screened out of the main I-SPY 2 trial. As a secondary aim, many biomarkers