The Department of Neurology at the University of Maryland School of Medicine (George Uhl MD PhD PI) is recruiting for highly qualified postdoctoral researchers. Researchers will aid work that is developing new small molecules toward use in humans. They will aid understanding of the novel targets that have been identified in human genome wide association and confirmatory mouse model experiments. Major current foci: inhibitors and substrate-selective positive allosteric modulators of the receptor type protein tyrosine phosphatase, PTPRD, as novel therapeutics for addictions and Alzheimer's disease neurofibrillary pathology, respectively. (see Uhl et al, PNAS 2018 for lead compound PTPRD phosphatase inhibitor).

We seek highly motivated scientists with PhD and/or MD in an appropriate field. Experience in molecular biology, biochemistry, molecular genetics, mouse behavioral assays as well as willingness to learn associated areas are positives. We are interested in researchers who can work well independently and in collaboration with University and VA researchers with medicinal chemistry, behavioral, molecular genetic, neurology and drug development backgrounds.

UMB is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to sex, gender identity, sexual orientation, race, color, religion, national origin, disability, protected Veteran status, age, or any other characteristic protected by law or policy.

UMB was ranked one of America's Best Large Employers by Forbes Magazine (Feb 2021).

Individuals who are interested should submit a detailed CV, a brief statement including, interests and skills, and the names of three references, and a short description of their doctoral training and career goals to:

George Uhl MD PhD FANA FACNP

Neurology, University of Maryland and VAMHCS (BT/127)

Suite 4A-150

10 North Greene Street

Baltimore, MD 21201

Preferred: Email to george.uhl@va.gov