An NIH-funded postdoctoral fellow position is available to study the mechanisms underlying gene-environment interactions leading to Congenital Heart Defects. The Zohn laboratory has established a new mouse model to study the mechanisms underlying gene-environment interactions and congenital heart defects. This project aims to achieve two objectives: 1) to determine how gene-environment converges on cardiac progenitors to cause CHDs and 2) to elucidate how diverse genetic mutations interact differently with environmental factors. To address these questions, the project will utilize sophisticated mouse genetics, gene expression, scRNAseq, bioinformatic, and phenotypic analysis. While previous experience with these approaches is appreciated, it is not necessary because my laboratory