RESEARCH FELLOW-Enhancer dysregulation in leukemia and lymphoma
University of Michigan - Ann Arbor
Location: Ann Arbor, Michigan
Internal Number: 241127
The laboratory of Dr. Russell Ryan in the University of Michigan Medical School Department of Pathology is seeking a highly motivated postdoctoral fellow with experience in epigenomics, transcriptional regulation, and / or cancer biology. The Fellow will conduct research scholarship focused on targeting chromatin regulation as a strategy for treatment of leukemias and / or lymphomas, with a particular focus on distal enhancers. The Fellow will plan, conduct, and analyze research experiments under the guidance of Dr. Ryan. The Fellow will collaborate with and assist in the mentorship of other lab members. The Fellow will author research manuscripts for submission to academic journals, and present findings in academic conferences. This is an annual appointment with the possibility of renewal contingent upon satisfactory performance and the availability of funding.
The successful applicant will conduct focused, hypothesis-driven research projects with the goal of publishing high-quality original research in the field of leukemia / lymphoma epigenetics. The fellow must be able to work collaboratively, and will supervise and mentor junior colleagues as part of their career development.
Applicants should possess a Ph.D. in a related field, with a solid publication track record, and should demonstrate excellent oral communication and scientific writing skills. Prior experience with mammalian cell culture and lentiviral transduction is required and experience working with mouse models is highly desirable. Other required skills include experience with next-generation sequencing library preparation, as well as chromatin assays, shuch as assays for chromatin accessibility (ATAC-Seq), protein binding (ChIP-Seq / ChIP-PCR, CUT&RUN), and genome topology (e.g. chromosome conformation capture). Experience with tools for bioinformatic analysis (Linux, R, Python) is required.
Please submit cover letter, CV, and contact information for 2-3 references combined into one PDF file by e-mail to: firstname.lastname@example.org
Contact: Russell J.H. Ryan, MD
Assistant Professor of Pathology, University of Michigan
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