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Life Science Research Professional 1
The Mahaney Laboratory in the Department of Neurosurgery at Stanford University School of Medicine studies the intraventricular hemorrhage (IVH)-induced post-hemorrhagic hydrocephalus (PHH) and has demonstrated that elevated levels of hemoglobin and ferritin in the CSF of preterm neonates are associated with development of PHH and severe ventricular enlargement. Our research currently focuses on (1) discovering CSF biomarkers for prediction and early diagnosis of PHH in neonates with IVH and (2) developing novel therapies with our animal hydrocephalus model that is equivalent to the brain maturity of human preterm neonates (i.e., 33 to 36 weeks' gestation in humans). Our goal is to translate the results from our studie
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