The Department of Genetic Medicine is seeking a Sr. Research Specialist for the growing new laboratory of Prof. Greg Newby, which is focused on the development and application of cutting-edge genome editing tools to mammalian cell and mouse models of genetic disease. The Sr. Research Specialist will be responsible for the scientific and administrative activities of the laboratory. Prior experience in genome editing methods is not required and training will be provided on the job. The position requires experience in molecular biology and genetics research and the ability to work well with collaborations and teams.
The position will have responsibility for the oversight of laboratory members, equipment, and reagents, as well as the ability to apply a wide range of sophisticated assays including RNA-seq, ChIP-seq, digital PCR, and bioinformatic analysis. The applicant should be comfortable with identifying, developing, and optimizing molecular biology assays. Administratively, the position involves the onboarding and oversight of other staff members, postdoctoral fellows, and graduate students.
Specific Duties & Responsibilities
Learn, perform, and train lab members in sophisticated laboratory methods to optimize and characterize genome editing outcomes (mammalian cell culture, isolation of DNA and RNA, PCR, digital or quantitative real-time PCR, DNA cloning, next-generation sequencing by Illumina and Oxford Nanopore, quantitative and qualitative analyses of DNA, RNA, and protein molecules).
Contributes to the maintenance of the laboratory, equipment, and supplies; conducts routine safety tests.
Maintains careful records of all samples obtained and experiments performed.
Independently assesses the quality of generated data and produces summary charts with statistical analyses.
Animal Model Responsibilities
Independently maintains mouse colonies; genotyping/weighing of mice.
Dissection of mice for anatomical, histological, and nucleotide sequencing studies.
Administrative Responsibilities: 25%
Responsible for budget management. Manages budgetary duties by ensuring charges, invoices, and orders are correctly routed to the proper grant.
Responsible for daily ordering of laboratory consumables, reagents, supplies, and equipment; maintains financial records.
Assists with drafting and refining scientific documents including manuscripts, grant applications, and letters of recommendation.
Ensures laboratory protocols and biosafety approvals are up-to-date.
Helps to hire, supervise, and train incoming laboratory members.
Advises personnel on proper laboratory techniques and use of laboratory equipment.
Ensures the laboratory and staff comply with annual safety inspections and safety office recommendations.
Special Knowledge, Skills, and Abilities
Experience with molecular biology techniques, cell culture, and mouse work (as above).
Must have a working knowledge of one or more of the following disciplines achieved through undergraduate studies and laboratory experience: biology, biochemistry, chemistry, physics, microbiology, and/or genetics.
Must be able to work in BSL2+ cell culture and mouse facilities.
Postdoctoral fellows and graduate students. Additional research staff hiring is planned as projects continue to ramp up.
$500,000 per year, makes purchasing decisions.
Bachelor's Degree in biology, chemistry, or related field.
Four years experience in a comparable laboratory performing relevant techniques.
Master's Degree, with related graduate research, may substitute for experience to the extent permitted by the JHU equivalency formula.
Experience with RNA-seq, ChIP-seq, ATAC-seq, or other high throughput genome analysis methods.
Classified Title: Sr. Research Specialist Role/Level/Range: ACRP/04/MC Starting Salary Range: Min. $47,500.00 - Max. $83,300.00 (Targeted $65,400.00, Commensurate with experience) Employee group: Full Time Schedule: Monday - Friday, 9:00 AM - 5:30 PM (4 weekdays including Monday and 1 weekend day. Other days are flexible) Exempt Status: Exempt Location: School of Medicine, East Baltimore Campus Department name: Genetics Institute of Genetic Medicine Personnel area: School of Medicine
Total Rewards The referenced salary range is based on Johns Hopkins University's good faith belief at the time of posting. Actual compensation may vary based on factors such as geographic location, work experience, market conditions, education/training and skill level. Johns Hopkins offers a total rewards package that supports our employees' health, life, career and retirement. More information can be found here: https://hr.jhu.edu/benefits-worklife/
Please refer to the job description above to see which forms of equivalency are permitted for this position. If permitted, equivalencies will follow these guidelines: JHU Equivalency Formula: 30 undergraduate degree credits (semester hours) or 18 graduate degree credits may substitute for one year of experience. Additional related experience may substitute for required education on the same basis. For jobs where equivalency is permitted, up to two years of non-related college course work may be applied towards the total minimum education/experience required for the respective job.
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