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Posted: 25-Aug-23
Location: Boston, Massachusetts
Salary: Open
Internal Number: 2023-36131
Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS and related diseases. We strive to create an inclusive, diverse, and equitable environment where we provide compassionate and comprehensive care to patients of all backgrounds, and design programs to promote public health particularly among high-risk and underserved populations. We conduct groundbreaking research that advances treatment, we educate tomorrow's physician/researchers, and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.
The Rowe Lab is interested on understanding how early life development impacts the function of immune cells, known as T cells in children. In young individuals T cells have different function and differentiation fates than those from adult individuals. Our lab utilizes a combination of cellular immunology, transcriptomic, and metabolomic tools to understand the biology behind this developmentally mediated regulation of immune cell fate. We are generating foundational studies to understand the how these processes, occurring naturally during childhood, impact the ability of children???s immune systems to protect them from infections and pediatric cancers. We use a combination of primary human samples and??in vivo??mouse models of diseases to answer these questions related to childhood health. The long-term goals of these studies is to identify unique features of the pediatric immune system that can be utilized to improve immune therapy strategies against cancer and infections or augmented to treat autoimmune diseases.??
Characteristics:
- Willing to learn the techniques of the laboratory and be the primary driver of postdoctoral project.
- Well organized with good written and verbal communication skills
- Will be require to present research findings at departmental seminars
- Comfortable with small animal (mouse) handling, breeding, tissue collection, and procedures is expected.
- Learn to manage small breeding colony of genetically modified mice.
- Use of electronic lab notebook system is required.
- Ph.D in biological sciences or equivalent
- Experience with flow cytometry (up to 18 colors utilized)
- Experience with molecular biology preferred (PCR, DNA/RNA collection, library preparation for sequencing).
- Interest or experience in learning bioinformatic analysis is preferred.
- Interest or experience in learning metabolomics is a preferred.
At Dana-Farber Cancer Institute, we work every day to create an innovative, caring, and inclusive environment where every patient, family, and staff member feels they belong.?? As relentless as we are in our mission to reduce the burden of cancer for all, we are equally committed to diversifying our faculty and staff.?? Cancer knows no boundaries and when it comes to hiring the most dedicated and diverse professionals, neither do we. If working in this kind of organization inspires you, we encourage you to apply.
Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other groups as protected by law.
