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Posted: 08-Aug-23
Location: Ann Arbor, Michigan
Salary: Open
Internal Number: 237932
A cover letter is required for consideration for this position and should be attached as the first page of your resume. The cover letter should address your specific interest in the position and outline skills and experience that directly relate to this position.?
A postdoctoral position is available in a dynamic research laboratory in the Department of Radiology at Michigan Medicine. Our group, led by Dr. Stefanie Galban, focuses on developing and establishing mouse models of various malignancies recapitulating human disease to develop novel therapies, including gene therapy and imaging technologies. Central to our studies is the lethal pediatric brain tumor, Diffuse Intrinsic Pontine Glioma (DIPG), particularly targeting cancer stem cells to address treatment resistance and identify new therapeutic paradigms in this disease. Our laboratory is surrounded by a rich research environment at the Center for Molecular Imaging and the Rogel Cancer Center. The postdoctoral fellow will support our investigations of mechanisms of molecularly targeted therapies utilizing imaging in cell cultures and mouse models. The research will involve molecular and cell biology procedures, gene editing techniques, protein analysis, DNA and RNA sequencing, fluorescence and bioluminescence imaging, and multi-modality imaging studies in mouse models of various cancers.
The candidate is expected to design and perform experiments to accomplish lab goals, critically analyze data, and take primary responsibility for writing and publishing results in scientific journals. The postdoctoral researcher will be expected to coordinate efforts with researchers in other scientific disciplines. The candidate must be open to a flexible schedule to accommodate times for animal imaging and varying treatment schedules.
Members of the Galban Laboratory work in a highly collaborative research environment with leading experts in oncology and imaging. Our goal is to motivate and train postdoctoral fellows across disciplines to address new and challenging problems in cancer and develop novel therapies.
70%- Molecular and cell biology animal experiments
- Design and perform experiments
- Coordinate research efforts with researchers in other scientific disciplines
- Cell-based assays
- Gene editing
- Molecular biology
- DNA and RNA sequencing
- Immunohistochemistry
20%- Imaging experiments
- Conduct multi-modality imaging studies in mouse models of various cancers
- MRI, CT, bioluminescence and fluorescence imaging
10%- Technical
- Analyze experimental data and interpret results to write summary reports and findings
- Prepare manuscripts for publication.
- Write and prepare abstracts and presentations for professional meetings
Highly motivated and enthusiastic individual with an MD/PhD or PhD background in cell and molecular biology, signal transduction, CRISPR gene editing, and RNA sequencing, along with a record of research excellence as demonstrated by peer-reviewed publications and scientific productivity. The candidate must have a strong desire and motivation to apply and translate research from cells to animal models using in vivo imaging techniques. The candidate must work well in a team of multidisciplinary researchers, have excellent organizational and communications skills in English, and competence in word processing and spreadsheet software.
Previous PhD or postdoctoral research experience in pediatric brain tumors.
One-year postdoc with option to renew.
Michigan Medicine conducts background screening and pre-employment drug testing on job candidates upon acceptance of a contingent job offer and may use a third party administrator to conduct background screenings. Background screenings are performed in compliance with the Fair Credit Report Act. Pre-employment drug testing applies to all selected candidates, including new or additional faculty and staff appointments, as well as transfers from other U-M campuses.
Michigan Medicine improves the health of patients, populations and communities through excellence in education, patient care, community service, research and technology development, and through leadership activities in Michigan, nationally and internationally. Our mission is guided by our Strategic Principles and has three critical components; patient care, education and research that together enhance our contribution to society.
Job openings are posted for a minimum of seven calendar days. The review and selection process may begin as early as the eighth day after posting. This opening may be removed from posting boards and filled anytime after the minimum posting period has ended.
The University of Michigan is an equal opportunity/affirmative action employer.
