The Department of Ophthalmology is seeking a full time Staff Associate to work under the direction of the Principle Investigator, performs duties associated with projects aiming to use gene therapy to tackle inherited retinal disorders (IRDs). Research approaches include gene augmentation, genome editing, in vivo studies in IRD mouse models, and induced pluripotent stem cell (iPSC) retinal organoid modeling.
Job Responsibilities:
· Provide general laboratory assistance to support research activities
· Conduct research experiments in accordance with laboratory and safety protocols
· Performs assignments which are non-routine and vary in complexity
· Complies data and computes results for a variety of research procedures, tests, and techniques
· Maintaining in vitro cultures, mice colony maintenance and procedures with mice such as injections and surgeries, experiments with animal tissues, sample collection and maintaining records
· Performing characterization of retinal function and structure in rodent models (ERG,OCT, fundoscopy, behavior testing), gene therapy and/or virology
· Preparing buffers, media, and running the in vitro and in vivo assays
· Cell and molecular biology experiments related to DNA, RNA and protein from cell, animal or clinical specimen.
· Differentiations and maintenance of retinal organoids from iPSCs
· Maintain records of experiment results, data management, ordering supplies, update inventory,
· organizing lab
· Maintenance of equipment
Minimum Qualifications:
· Bachelor's degree in Biology, chemistry or related science or equivalent combination of education, training and experience
· Working knowledge of laboratory equipment and research protocols
· Ability to work with animal experiments
· Knowledge of computer analysis techniques
· Ability to provide routine analysis and interpretation of research data
Preferred Qualifications:
· Two years of research experience in basic science research
Salary Range: $58,710 - $58,710
Columbia University is an Equal Opportunity Employer / Disability / Veteran
Pay Transparency Disclosure
The salary of the finalist selected for this role will be set based on a variety of factors, including but not limited to departmental budgets, qualifications, experience, education, licenses, specialty, and training. The above hiring range represents the University's good faith and reasonable estimate of the range of possible compensation at the time of posting.
Columbia University is one of the world's most important centers of research and at the same time a distinctive and distinguished learning environment for undergraduates and graduate students in many scholarly and professional fields. The University recognizes the importance of its location in New York City and seeks to link its research and teaching to the vast resources of a great metropolis. It seeks to attract a diverse and international faculty and student body, to support research and teaching on global issues, and to create academic relationships with many countries and regions. It expects all areas of the university to advance knowledge and learning at the highest level and to convey the products of its efforts to the world.