The Concepcion laboratory at Columbia University Irving Medical Center seeks a full-time Postdoctoral Research Scientist to join a growing research team focused on epigenetic deregulation in lung cancer. Our laboratory is interested in understanding how alterations in chromatin state shape tumor cell fate throughout tumor evolution. Areas of investigation include: 1) understanding how mutations in chromatin regulators alter the chromatin landscape to facilitate malignant transformation; 2) investigating gene regulatory programs co-opted by cancer cells throughout tumor progression, and 3) identifying dependencies and targetable features of lung cancers harboring specific mutations in chromatin regulators. To this end, we use a combination of genetically engineered mouse models, organoids, and patient-derived samples and leverage cutting-edge approaches in gene editing, organoid technologies, and various -omics.
The candidate will train in a highly supportive and collaborative research environment in the vibrant scientific environment at Columbia University which includes the Department of Molecular Pharmacology & Therapeutics and the Herbert Irving Comprehensive Cancer Center. The candidate will work with a growing team of cancer researchers and have the opportunity to attend and present at scientific conferences, interact with industry on projects spanning basic and translational science, mentor students, and engage with the patient community.
We are particularly looking for candidates with training in computational biology that are interested in both computational and bench work. This is an ideal position for a computational biology PhPh.D.eeking to gain more experience in cancer research in a supportive environment.
Minimum Degree Required
Ph.D., MD, or equivalent doctoral degree
Experience in molecular and cellular biology, 2D and organoid culture systems, generation, and analyses of mouse models of cancer, -omic technologies
Training in bioinformatics
Excellent scientific and interpersonal communication skills
Columbia University is an Equal Opportunity Employer / Disability / Veteran
Pay Transparency Disclosure
The salary of the finalist selected for this role will be set based on a variety of factors, including but not limited to departmental budgets, qualifications, experience, education, licenses, specialty, and training. The above hiring range represents the University's good faith and reasonable estimate of the range of possible compensation at the time of posting.
Columbia University is one of the world's most important centers of research and at the same time a distinctive and distinguished learning environment for undergraduates and graduate students in many scholarly and professional fields. The University recognizes the importance of its location in New York City and seeks to link its research and teaching to the vast resources of a great metropolis. It seeks to attract a diverse and international faculty and student body, to support research and teaching on global issues, and to create academic relationships with many countries and regions. It expects all areas of the university to advance knowledge and learning at the highest level and to convey the products of its efforts to the world.