The Applied Genomics, Computation & Translational Core is looking for a Biomedical Specialist to join the team!
The Cedars-Sinai Applied Genomics, Computation, and Translational Core (AGCT Core) is a fully equipped, state-of-the-art genomics facility offering data generation and interpretation for basic science and translational research in next-generation sequencing technologies, including single cell omics, spatial transcriptomics, and bulk cell omics. We specialize in single cell omics and spatial transcriptomics via the 10x Genomics, Parse Biosciences, Mission Bio, and NanoString platforms. Our R&D team offers sample preparation for single cell assays, such as nuclei isolation from frozen tissue or single cell isolation from fresh tissue dissociation. The AGCT Core also offers comprehensive services for standard bulk cell sequencing in genomics, transcriptomics, epigenomics, and metagenomics. To learn more please visit Applied Genomics, Computation & Translational Core | Cedars-Sinai.
Are you ready to be a part of breakthrough research?
The Genomics Core Biomedical Specialist is responsible for carrying out wet lab procedures involving DNA/RNA isolation from various sources such as cells, tissue, FFPE curls and scrapes, and blood. In addition, they possess expertise in the complete Next-Generation Sequencing (NGS) workflow, which includes DNA/RNA quantification and quality control (QC) analysis, manual library preparation, library quantification and QC analysis, sequencing on the Illumina platform, and analysis of sequencing metrics.
As part of their duties, the Biomedical Specialist will ensure accurate and up-to-date electronic documentation using an electronic lab notebook, project management software, and laboratory information management system. They will also manually prepare libraries for bulk cell, single cell, and spatial omics, covering transcriptomics (RNA-Seq), genomics (WGS/WES), epigenomics (WGBS, ATAC-Seq), and metagenomics (16S/ITS amplicon sequencing, shotgun).
Overall, this position involves hands-on work in a wet lab environment, focusing on DNA/RNA isolation and various aspects of the NGS workflow, as well as documentation and library preparation for different omics applications.
Primary Duties and Responsibilities:
Train, guide, and supervise a team of junior associates.
Train and supervise junior associates on Next-Generation Sequencing experiments, procedures, and day-to-day service request fulfillment and lab operations.
Effectively communicate needs and requirements to junior associates as required for the management of service requests and day-to-day lab operations.
Manage junior associate performance, mentor and coach, and seek opportunities to help them grow and become their best.
Assign service requests to junior associates and ensure their proper execution and successful completion.
Ensure the availability of all required resources for the execution of service requests.
Liaise with investigators regarding service requests.
Participate in the planning, execution, and troubleshooting of service requests.
Provide research and input on new technologies and assays for testing to possibly develop and implement new service offerings.
Execute or manage the execution of projects testing new technologies, assays, or kits.
Analyze, summarize, and present findings at monthly R&D meetings.
Assist with the implementation of new technologies, assays, or kits into new service offerings by writing and reviewing standard operating procedures, service guidelines, and staff training guides, and training junior associates.
Receive, store, and document samples.
Attend meetings and seminars/webinars as assigned.
Bachelor of Sciences in Genetics, Genomics, Molecular Biology, or Biological Sciences is required. Master's degree is preferred.
Experience & Skills:
Two (2) years of laboratory experience are required. Five (5) years is preferred.
Minimum 3 years of experience performing NGS library preparation in bulk cell genomics, transcriptomics, and metagenomics.
Minimum 2 years of experience in the operation of Illumina sequencers and Agilent Technologies fragment analyzers.
Minimum 1 year of supervisory and training experience.
Experience in single cell NGS assays and cell biology is preferred.
Critical analysis, problem-solving, troubleshooting, multitasking, time management, following through tasks with details, working independently with minimal supervision.
Interact with professionalism with teammates, peers, researchers, investigators, and support staff of diverse backgrounds and educational levels.
Respond to rapidly changing priorities and exceptionally diverse demands through constant interruptions in a fast-paced laboratory environment.
Must be self-motivated, take initiative, enjoy learning, and willing to take on new challenges while independently executing new or unusual and complex technical procedures and protocols.
Work cooperatively with other personnel as part of a team to accomplish daily and weekly goals.
Proficient in PC (or Mac) skills as well as demonstrated proficiency in Microsoft Word, Excel, and PowerPoint.
Working Title: Biomedical Specialist - Applied Genomics, Computation & Translational Core Department: BMS - Bioinfo & Func Genomics Business Entity: Cedars-Sinai Medical Center Job Category: Biomanufacturing Job Specialty: Biomanufacturing Position Type: Full-time Shift Length: 8 hour shift Shift Type: Day Base Pay:$73,400.00 - $113,600.00
Providing healthcare for more than 100 years, Cedars-Sinai has evolved into one of the most dynamic and highly renowned medical centers in the world. Along with caring for patients, Cedars-Sinai is a hub for biomedical research and a training center for future physicians and other healthcare professionals. This attracts exceptional talent to Cedars-Sinai, including world-renowned physician-scientists who seek a place where they can both conduct research and see patients--the ideal formula for discovery and its translation into cures. Our patients benefit from access to doctors at the top of their fields, and our researchers have an ideal community in which to study the impact of healthcare challenges, and reflect that knowledge in their research. The greater Los Angeles area in which Cedars-Sinai resides possesses unparalleled cultural and ethnic diversity which offers outstanding oppor...tunities for translational and clinical research and a dynamic environment for medical education.Although community based, Cedars-Sinai is a major teaching hospital affiliated with the David Geffen School of Medicine at the University of California, Los Angeles (UCLA). Cedars-Sinai has highly competitive graduate medical education programs in more than 50 specialty and subspecialty areas, a graduate program in biomedical sciences and translational medicine, a clinical scholars program directed towards junior physicians with aspirations to become clinical scientists, and post graduate training opportunities.There are more than 250 full-time faculty members at Cedars-Sinai. The voluntary medical staff, comprised of more than 2,200 specialty board-certified or board-qualified physicians, represent all of the specialties and subspecialties and collaborate with full-time medical staff in the teaching responsibilities of the graduate medical education programs.