The Cruchaga Lab, member of the NeuroGenomics and Informatics Center, (NGI) at Washington University School of Medicine is recruiting a Bioinformatics Scientist. We are seeking an experienced, self-motivated, self-driven scientist to work as a part of vibrant group in a fast-paced environment. The new Bioinformatics Scientist should have wide and solid expertise in WES/WGS, GWAS and/or RNA-seq data analyses to work and lead several projects on the identification of genes dysregulated in Alzheimer disease. Will work in a collegial environment and join a multidisciplinary, diverse team in a well-stablished, well-funded research group, currently 30+ dynamic members, developing bioinformatics and analyzing multi omics data to explore the frontiers of neurodegenerative diseases.
The NGI generates and analyzes Whole-Genome and high-throughput multi-dimensional omics data to study neurodegenerative diseases of the central nervous system with emphasis on Alzheimer's and Parkinson's diseases. The goal of our research is to use genomic and multi-omic approaches to understand the biology of Alzheimer's and Parkinson diseases. Our labs have pioneered the use of new biomarkers as endophenotypes for genetic studies.
Primary Duties and Responsibilities
Independently develop a wide variety of computer programs to meet the needs of data collection, quality control, analysis and report generation.
Lead and manage research projects and work together with junior members to complete data processing and analysis following specific timelines.
Lead complex data analysis and writes interpretative reports for Principal investigators.
Lead and collaborate within cross-functional teams.
Lead analytical support for internal projects and external collaborations.
Supervise database structure: includes updating, validating, curating and harmonizing longitudinal, cross-sectional data from different sources.
Provide a centralized, confidential and secure access to phenotypic data to Principal investigators.
Lead the response to data queries from Principal Investigators and external collaborators.
Create reports and prepare highly technical presentations.
Write manuscripts and communications for conference presentations.
Present data in meetings and conferences.
Other duties as assigned.
PhD degree in Neurogenetics, Bioinformatics, Computational Biology, Statistical Genetics, Biostatistics, Medical Statistics, Neuroscience, Genetics, Statistics, Mathematics or related.
At least six years of experience working in genomics with large datasets, preferably in a research environment.
Proficiency in scientific programming languages (e.g., Python, R, Perl, Java), in a UNIX/Linux and/or Windows environment.
Strong background in PLINK, QC, IBD, PCA; R, bash and excel (Python, Perl, SAS, SQL, Docker are a plus) or other analyses toolset.
Knowledge of association analyses, PRSice, MAGENTA, Mendelian Randomization, MANTRA, Coloc, QTL and Unix/Linux.Â
Excellent communication and problem solving skills.
Familiar working in cross-functional teams.
Knowledge of neuroscience and neurodegeneration is highly beneficial.Â
Good understanding of computational biology and flexibility to work within a large dynamic scientific team.
PhD degree in computer science, bioinformatics, biostatistics, or related field, plus six years of experience; or a master's degree in computer science, bioinformatics, biostatistics, or a related field plus ten years of experience.Â
$70,100.00 - $127,100.00 / AnnuallyThe salary range reflects base salaries paid for positions in a given job grade across the University. Individual rates within the range will be determined by factors including one's qualifications and performance, equity with others in the department, market rates for positions within the same grade and department budget.
If you are unable to use our online application system and would like an accommodation, please emailÂ CandidateQuestions@wustl.eduÂ or call the dedicated accommodation inquiry number at 314-935-1149 and leave a voicemail with the nature of your request.
All external candidates receiving an offer for employment will be required to submit to pre-employment screening for this position. The screenings will include criminal background check and, as applicable for the position, other background checks, drug screen, an employment and education or licensure/certification verification, physical examination, certain vaccinations and/or governmental registry checks. All offers are contingent upon successful completion of required screening.
Up to 22 days of vacation, 10 recognized holidays, and sick time.
Competitive health insurance packages with priority appointments and lower copays/coinsurance.
Want to Live Near Your Work and/or improve your commute? Take advantage of our free Metro transit U-Pass for eligible employees. We also offer a forgivable home loan of up to $12,500 for closing costs and a down payment for homes in eligible neighborhoods.
WashU provides eligible employees with a defined contribution (403(b)) Retirement Savings Plan, which combines employee contributions and university contributions starting at 7%.
Wellness challenges, annual health screenings, mental health resources, mindfulness programs and courses, employee assistance program (EAP), financial resources, access to dietitians, and more!
We offer 4 weeks of caregiver leave to bond with your new child. Family care resources are also available for your continued childcare needs. Need adult care? Weâ™ve got you covered.
WashU covers the cost of tuition for you and your family, including dependent undergraduate-level college tuition up to 100% at WashU and 40% elsewhere after seven years with us.
Washington University in St. Louis is committed to the principles and practices of equal employment opportunity and especially encourages applications by those from underrepresented groups. It is the Universityâ™s policy to provide equal opportunity and access to persons in all job titles without regard to race, ethnicity, color, national origin, age, religion, sex, sexual orientation, gender identity or expression, disability, protected veteran status, or genetic information.
Washington University is dedicated to building a diverse community of individuals who are committed to contributing to an inclusive environment â“ fostering respect for all and welcoming individuals from diverse backgrounds, experiences and perspectives. Individuals with a commitment to these values are encouraged to apply.
Washington University in St. Louis, a medium-sized, independent university, is dedicated to challenging its faculty and students alike to seek new knowledge and greater understanding of an ever-changing, multicultural world. The University offers more than 90 programs and almost 1,500 courses leading to bachelor's, master's and doctoral degrees in a broad spectrum of traditional and interdisciplinary fields, with additional opportunities for minor concentrations and individualized programs. The faculty is composed of scholars, scientists, artists and members of the learned professions. They serve society by teaching; by adding to the store of human art, creativity, understanding, and wisdom; and by providing direct services, such as health care.