Basic Life Research Scientist (3 Year Fixed Term with Possible Extension)
Location: Stanford, California
Internal Number: 92863
Summary We are seeking 2 talented and motivated bioinformatics specialists to be appointed as Basic Life Research Scientists at 100% FTE for a 3-year fixed term (possibility for renewal). The successful candidates will have expertise in bioinformatics/systems biology with a focus on analyzing omics data, including gene expression profiling, and will work in Dr. Bali Pulendran's laboratory at the Institute for Immunity, Transplantation, and Infection at Stanford University. The individuals will join a dynamic, interdisciplinary group of researchers including immunologists, vaccinologists, clinicians, and bioinformaticians, to address major global health issues relating to vaccines and infectious diseases, funded by the National Institutes of Health and the Bill and Melinda Gates Foundation. The successful applicants will perform integrative analysis of omics profiling of the transcriptome, epigenome, and metabolome to discover biomarkers of vaccine efficacy and new biological insights about the human immune system.
Responsibilities The successful candidates will both lead and collaborate on projects aimed to using systems biological approaches to define the correlates and mechanisms of immunity to vaccination.
Analyze and integrate omics datasets from multiple platforms (single cell RNA sequencing, single cell ATAC-sequencing, multidimensional flow cytometry and metabolomics).
Work with a multi-disciplinary team of immunologists, clinicians and bioinformaticians to apply novel and complex statistical approaches to immunological data generated in clinical studies.
Contribute to the development of bioinformatics workflows and pipelines.
Collaborate with experimental immunologists in the analysis and visualization of omics data.
Maintain a database of omics data generated in the lab.
As an organization that receives federal funding, Stanford University has a COVID-19 vaccination requirement that will apply to all university employees, including those working remotely in the United States and applicable subcontractors. To learn more about COVID policies and guidelines for Stanford University Staff, please visit https://cardinalatwork.stanford.edu/working-stanford/covid-19/interim-policies/covid-19-surveillance-testing-policy
Requirements The qualified applicants will have:
A Ph.D. in bioinformatics, computational biology, computer science, or in a relevant biological discipline.
Demonstrated experience in bioinformatics research, focusing on transcriptional profiling and predictive modeling.
Familiarity with working in a Linux/Unix environment; experience is Linux system administration and hardware configuration is a plus.
Experience with development and maintenance of relational databases.
Fluency in at least one programming language (R, Python, Perl, Matlab).
Adequate knowledge of molecular biology, and intention to deepen and improve his/her understanding of these fields. Knowledge in immunology is preferred though not essential.
Expert knowledge of bioinformatics applications and biological databases.
Strong quantitative or statistical background, experience in machine learning and predictive modeling are highly desirable.
Excellent verbal and written communication skills.
Excellent opportunities and competitive salaries, and the opportunity to work at the cutting edge of human immunology in a stimulating, diverse and exciting research environment is offered.
Stanford is an equal employment opportunity and affirmative action employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other characteristic protected by law. Stanford welcomes applications from all who would bring additional dimensions to the University's research, teaching and clinical missions.
Why work at Stanford?Stanford University has changed the world, over and over again.We are one of Silicon Valley's largest employers - and also one of the most unique. Our mission is to educate future leaders and promote interdisciplinary, world-class research and teaching. This passion makes Stanford an intensely creative, rewarding, and challenging place to work. At the same time, our traditions of respect and collaboration sustain a humane, supportive environment in which to pursue your life and your career.At Stanford you'll work with bright, diverse, dedicated people. You'll find encouragement to learn and grow. You'll enjoy excellent benefits and an outstanding environment. How will it change you?