The Department of Genetics at Stanford University is seeking a Life Science Research Professional 1 to join the Genomics Mapping Center of the Snyder laboratory. The LSRP will be a member of a research team that is using cutting edge technologies, such as CRISPR/Cas9 cell line editing, ChIP-seq, ATAC-seq, single cell genomics and high throughput sequencing, to map regulatory elements in the human genome. The goal of this work is to help understand the biology of gene regulation in the human genome by providing high quality transcription factor binding and chromatin accessibility data to the research community.
Responsibilities include maintenance of human cell lines including stem cells, basic and advanced molecular biology (such as primer design, PCR, immunoblots, ChIP-seq, ATAC-seq), and other duties as assigned. The LSRP is expected to follow standard operating procedures (SOPs) and to keep detailed records using a laboratory management system (LIMS). The LSRP will work closely with other members of the research team and the supervisor to develop protocols, interpret and analyze the results of experiments, and suggest modifications to procedures as appropriate.
The candidate must be organized, enjoy problem solving, be a team player and have strong communication skills. This is an opportunity for a motivated and reliable person to participate in highly collaborative, cutting-edge research at the forefront of modern biology.
Duties include:
- Plan approach to experiments in support of research projects in lab based on knowledge of scientific theory.
- Independently conduct experiments; maintain detailed records of experiments and outcomes.
- Apply the theories and methods of a life science discipline to interpret and perform analyses of experiment results; offer suggestions regarding modifications to procedures and protocols in collaboration with senior researcher.
- Review literature on an ongoing basis to remain current with new procedures and apply learnings to related research.
- Contribute to publication of findings as needed. Participate in the preparation of written documents, including procedures, presentations, and proposals.
- Help with general lab maintenance as needed; maintain lab stock, manage chemical inventory and safety records, and provide general lab support as needed.
- Assist with orientation and training of new staff or students on lab procedures or techniques.
*- Other duties may also be assigned.
DESIRED QUALIFICATIONS:
- Bachelor's degree in Biology, Genetics, Molecular Biology, or related scientific field is preferred.
- Previous laboratory research experience in academia or industry desired.
- Experience with tissue culture techniques, especially cultivation of human stem cells.
- Proficiency with basic molecular biology techniques, such as plasmid preparation, PCR, and immunoblots.
- Meticulous record keeping and organizational skills. Experience with Standard operating procedures (SOPs) is a plus.
- Careful attention to detail in all laboratory techniques, high-throughput mindset.
- Strong analytical skills and excellent judgment.
- Ability to work as part of a team and coordinate experiments with co-workers is essential.
EDUCATION & EXPERIENCE (REQUIRED):
Bachelor's degree in related scientific field.
KNOWLEDGE, SKILLS AND ABILITIES (REQUIRED):
- General understanding of scientific principles. Demonstrated performance to use knowledge and skills when needed.
- Demonstrated ability to apply theoretical knowledge of science principals to problem solve work.
- Ability to maintain detailed records of experiments and outcomes.
- General computer skills and ability to quickly learn and master computer programs, databases, and scientific applications.
- Ability to work under deadlines with general guidance.
- Excellent organizational skills and demonstrated ability to accurately complete detailed work.
CERTIFICATIONS & LICENSES:
None.
PHYSICAL REQUIREMENTS*:
- Frequently stand, walk, twist, bend, stoop, squat, grasp lightly, use fine manipulation, grasp forcefully, perform desk-based computer tasks, use telephone, write by hand, lift, carry, push and pull objects weighing over 40 pounds.
- Occasionally sit, kneel, crawl, reach and work above shoulders, sort and file paperwork or parts.
- Rarely climb, scrub, sweep, mop, chop and mix or operate hand and foot controls.
- Must have correctible vision to perform duties of the job.
- Ability to bend, squat, kneel, stand, reach above shoulder level, and move on hard surfaces for up to eight hours.
- Ability to lift heavy objects weighing up to 50 pounds.
- Ability to work in a dusty, dirty, and odorous environment.
- Position may require repetitive motion.
*- Consistent with its obligations under the law, the University will provide reasonable accommodation to any employee with a disability who requires accommodation to perform the essential functions of his or her job.
WORKING CONDITIONS:
- May require working in close proximity to blood borne pathogens.
- May require work in an environment where animals are used for teaching and research.
- Position may at times require the employee to work with or be in areas where hazardous materials and/or infectious diseases are present.
- Employee must perform tasks that require the use of personal protective equipment, such as safety glasses and shoes, protective clothing and gloves, and possibly a respirator.
- May require extended or unusual work hours based on research requirements and business needs.
WORK STANDARDS (from JDL):
- Interpersonal Skills: Demonstrates the ability to work well with Stanford colleagues and clients and with external organizations.
- Promote Culture of Safety: Demonstrates commitment to personal responsibility and value for safety; communicates safety concerns; uses and promotes safe behaviors bases on training and lessons learned.
- Subject to and expected to comply with all applicable University policies and procedures, including but not limited to the personnel policies and other policies found in the University's Administrative Guide, http://adminguide.stanford.edu.
