Career Center

POSTDOCTORAL POSITIONS AVAILABLE IN THE ICG – Pasqualucci Lab

Postdoctoral Research Scientist positions are available immediately for MD and/or PhD recipients interested in studying genetics and epigenetics-driven mechanisms implicated in the pathogenesis of mature B cell lymphomas in the Pasqualucci Lab at Columbia University's Institute for Cancer Genetics.

Postdocs will conduct research on the role of lymphoma-associated mutations in the malignant transformation of germinal center B cells, with emphasis on those targeting histone/chromatin modifier genes. Examples include mechanisms by which inactivation of the KMT2D/KMT2C methyltransferases (Zhang et al, Nature Medicine 2015) and the CREBBP/EP300 acetyltransferases (Zhang et al., Cancer Discovery 2017) contribute to the clonal evolution of the lymphoma precursor cell through cell-intrinsic and cell-extrinsic mechanisms, and the identification and targeting of synthetic lethal interactions in these tumors (Meyer et al, Immunity, 2019). Other projects focused on charting the genetic landscape of specific B cell lymphoma subtypes (e.g. Liu, Blood Cancer Discovery 2020), including the non-coding genome, and the interaction between gene mutations and the immune microenvironment are also ongoing. Candidates will have the opportunity to work in the vibrant environment of the Institute for Cancer Genetics and be integrated with an outstanding group of cancer biologists and bioinformaticians.

The ideal candidates must be highly motivated, enthusiastic, and capable of handling a fast-paced environment, with a proven track record of research and laboratory work in the form of publications in English language journals. A strong background in molecular biology with solid organizational, time management, and project management skills is required. Experience in genetics and chromatin analysis, B cell immunology, and mouse models will be a plus. Candidates are expected to be able to communicate in written and spoken English.

1. Full curriculum vitae, publication list, information on years of experience in research and laboratory work.
2. Names and contact information (email and telephone numbers) of 3 references.
3. Summary of research interests and long-term plans.

Please apply online and address any inquiries to Dr Laura Pasqualucci lp171@cumc.columbia.edu(link sends e-mail).

Salary Range $60,000 - $63,038

Columbia University is an Equal Opportunity Employer / Disability / Veteran

Pay Transparency Disclosure

The salary of the finalist selected for this role will be set based on a variety of factors, including but not limited to departmental budgets, qualifications, experience, education, licenses, specialty, and training.  The above hiring range represents the University's good faith and reasonable estimate of the range of possible compensation at the time of posting.

About Columbia University

Columbia University is one of the world's most important centers of research and at the same time a distinctive and distinguished learning environment for undergraduates and graduate students in many scholarly and professional fields. The University recognizes the importance of its location in New York City and seeks to link its research and teaching to the vast resources of a great metropolis. It seeks to attract a diverse and international faculty and student body, to support research and teaching on global issues, and to create academic relationships with many countries and regions. It expects all areas of the university to advance knowledge and learning at the highest level and to convey the products of its efforts to the world.

Connections working at Columbia University