Career Center

Post Doctoral Researcher to pursue specialized research training, education and experience under the guidance of a scientific mentor in the Division of Pulmonary, Critical Care and Sleep Medicine within the Department of Internal Medicine; plans, designs and executes experiments of considerable scope and complexity in the assigned research lab focusing on (Pulmonary biology) collects and analyzes data for research sponsored by appropriate agencies and Institutions; identifies and selects problems to be studied; develops and troubleshoots new experimental techniques and protocols; attends research seminars; contributes to manuscript preparation and supports technical writing; participates in preparation of grant applications for extramural funding; performs additional duties as assigned.

Minimum Education/Experience Requirements:

Doctoral degree in Biological Sciences required; Requires successful completion of a background check. Selected candidate may be requested to complete a pre-employment physical including a drug screen.

The Mebratu lab investigates the molecular mechanisms how Influenza A viruses hijack and subvert host cellular processes to facilitate viral replication since this information will be useful in developing therapeutic host targets to treat the disease. We use cutting-edge molecular, genetic and proteomic approaches 1) to study how IAV uses host cellular proteins to promote its replication and pathogenesis in human airway epithelial cells; 2) to identify specific domains of viral proteins that interact with host cellular proteins to establish persistent infection and viral replication; 3) investigate specific gene polymorphisms that contributes to influenza disease severity in humans; 4) to study how host cellular proteins promote lung inflammation in chronic lung disease in response to injury. Our approaches include biochemistry, molecular biology, mouse genetics, virology, and human genetics.

We invite an outstanding candidate with a strong background in molecular biology and/or immunology to join our NIH-funded research group to study the role of host cellular proteins in pulmonary inflammation and influenza A Virus pathogenesis. Experience in virology and mouse model of human diseases is a plus. The candidate will have an opportunity to learn or become more proficient in the techniques in rodent models of lung injury/inflammation, fluorescence imaging, flow cytometry, proteomics, transcriptomics, and standard biochemical/molecular approaches

Logo

About The Ohio State University

The Ohio State University is a dynamic community of diverse resources, where opportunity thrives and where individuals transform themselves and the world. Founded in 1870, Ohio State is a world-class public research university and the leading comprehensive teaching and research institution in the state of Ohio. With more than 63,000 students (including 57,000 in Columbus), the Wexner Medical Center, 14 colleges, 80 centers and 175 majors, the university offers its students tremendous breadth and depth of opportunity in the liberal arts, the sciences and the professions.

Connections working at The Ohio State University