SUBFUNCTION DEFINITION: Bioinformatics applies biology, computer science, data science, and statistics to analyze and interpret biological and clinical data.
Curate genomic and biological data from scientific literature using computer readable ontologies and defined syntax including: gene expression, genes, transgenic and mutant lines, experimental, reagents, anatomy, genotype, phenotype, GO-CAMs (gene ontology) and models of human disease.
Metadata curation of transcriptomic and epigenetic high-throughput datasets.
Participate in genome annotation and gene nomenclature.
Contribute to ontology development.
Develop strategies to improve workflow, data curation, data display and website design.
Help identify and implement efficiencies. Maintain standard operating procedures.
Foster and maintain effective communications with the research community, other resources and institutions.
Co-author reports and publications and give presentations at national and international meetings and workshops.
Curates, annotates and organizes various types of biomedical data (e.g., genomic, clinical, imaging, sequencing) in various formats (e.g., flat files, relational and non-relational databases). Collects and records appropriate metadata. Ensures data are securely stored yet highly accessible to authorized users.
Executes pipelines for curating, processing and analyzing biomedical data of various types (e.g., genomic, clinical, imaging, sequencing). Utilizes existing software to support complex data management tasks (e.g., sequence alignment, variant calling, inter-sample comparison, patient matching/linkage). Utilizes web-based bioinformatics tools and public/proprietary relational databases. Follows standard operating procedures. Works in collaboration with both technology and scientific teams.
Requirements Gathering Interfaces with clinicians/researchers to collect requirements of basic to moderate complexity including user workflows. Contributes to problem-solving and solution evaluation.
Software Evaluation & Development
Contributes to the evaluation and development of software solutions to support basic to moderately complex data workflows. Under general supervision, assists with implementation and testing efforts. Effectively communicates the status of all efforts to necessary parties. Utilizes project and time management skills to complete projects within specific timeframes.
Contributes to analyses and publications. Generates reports and figures for publications. Assists with materials for publications and scientific meetings. Works closely with biostaticians on the production of publication and presentation materials.
Bachelor of Science degree (MSc or PhD degree in biocuration and/or biomedical research preferred)
0 - 2 years of work experience in a related job discipline
Experience with genomics, developmental or cell biology research, particularly Xenopus.
Experience with data wrangling and programming languages such Perl, Python or R.
Experience working with ontologies, biocuration and/or biological knowledgebases.
Strong interpersonal and communication skills, including excellent written and spoken English.
Robust evidence of documentation for code and workflows.
Self-motivated with excellent time management skills.
Show ability to work in a team and independently.
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About Cincinnati Children's Hospital Medical Center
At Cincinnati Children’s, we come to work with one goal: to make children’s health better. We believe in a team approach, both in caring for patients and their families, and in advancing science and discovery. We strive to do better, and find energy and inspiration in our shared purpose. If you want to be the best you can be, you can do it at Cincinnati Children’s.