School of Medicine - Open Rank - Neuro-oncology and Neurovascular Research
University of Alabama, Birmingham
Location: Birmingham, Alabama
Internal Number: 18371
Position Number: 311360000.05753; 311360000.05760; 311360000.03005; 311360000.02201
School/College: School of Medicine
The Department of Neurosurgery in the School of Medicine at the University of Alabama at Birmingham (UAB) has very active and well-established programs in both neuro-oncology and cerebrovascular clinical research, and we are broadening our laboratory research effort in these areas. We are looking to recruit highly motivated individuals to fill the following 4 open research positions for investigators holding MD, PhD, or MD/PhD degrees:
Tenured Professor level Neuro-oncology Researcher
Assistant or Associate Professor level Neuro-oncology Researcher
Instructor level Neuro-oncology Researcher to work with Dr. James M. Markert
Assistant, Associate or Tenured Professor level Cerebrovascular Researcher The tenured and tenure track Neuro-oncology positions are open for broadly based research interests in the field of Neuro-oncology, including but not limited to both primary and metastatic adult brain tumors, genomics, proteomics/kinomics or epigenetics at the single cell level, immunobiology of host-tumor interactions and relevant patient-derived models of cancer. Successful applicants for the tenured and tenure-track Neuro-oncology positions will work in partnership with the UAB O'Neal Comprehensive Cancer Center Neuro-oncology Program. Added preference will be given to candidates whose research can synergize with existing UAB faculty to enable programmatic research support, e.g., multiple (principal) investigator grants.
The competitive candidate for the instructor Neuro-oncology position will have a research interest in primary and metastatic adult brain tumors, genomics, proteomics, kinomics and epigenetics, tumor immunology, and/or relevant patient-derived models of cancer. The major focus of the laboratory is oncolytic viral therapy and immunotherapy of cancers, for translational research. Applicants should be comfortable supervising and mentoring research staff, students, and residents. Common assays in the laboratory include tissue culture, viral culture, PCR, RT-PCR, cloning and oncolytic viral construction/engineering, ELISA, Western blotting, Southern blotting, mouse surgery and necropsy, flow cytometry, immunohistochemistry, and fluorescence microscopy. The laboratory also requires familiarity with biostatistics and enough familiarity with bioinformatics to be able to either code or work with UAB bioinformatics to perform a variety of clustering algorithms and deconvolution analyses to be performed on pre and post-treatment specimens. The laboratory is moving to a larger involvement in single-cell analyses and spatial transcriptomics and the successful candidate should be prepared to develop knowledge and skills in these areas.
Competitive candidates for the cerebrovascular position will have areas of interest that include but are not limited to: protective effects of ischemic preconditioning; endothelial dysfunction in ischemic and hemorrhagic stroke; role of inflammation in stroke, mechanisms of angiogenesis and arteriogenesis in chronic ischemia, and platelet/surface interaction. The successful applicant will join a productive and collaborative interdisciplinary research team consisting of investigators in the Departments of Neurosurgery, Neurology and Radiology at UAB. We will provide ample opportunity for developing independent work with state-of-the-art equipment, facilities, and analytical methods.
Ideally these positions will be filled by candidates devoting their full effort towards research, with no clinical duties. Fractional effort towards clinical duties is possible if it meshes with the plans of candidates seeking the tenured and tenure-track positions.
The University of Alabama at Birmingham (UAB) is a research university and academic health center that discovers, teaches, and applies knowledge for the intellectual, cultural, social, and economic benefit of Birmingham, the state, and beyond. UAB is internationally renowned for its intensely collaborative culture that has — for more than five decades — produced breakthroughs in education, health care, research, and service. UAB was ranked #1 in the United States, and in the top 10 worldwide, in the Times Higher Education World University Rankings, 2018 Young University Rankings.
UAB Medicine is the third largest public academic medical center in the country, with more than 1,900 beds and almost 18,000 employees. UAB Hospital is the centerpiece of the UAB Health System and is the teaching hospital for the UAB School of Medicine. Situated among major research centers and clinics, UAB Hospital provides patients with a complete range of primary and specialty care services, as well as the most up-to-date treatments and innovations in health care. In addition to UAB Hospital, UAB Medicine includes The Kirklin Clinicof UAB Hospital, UAB Callahan Eye Hospital, as well as several primary and specialty care clinics, a dozen member and affiliate hospitals within Alabama, more than 10 cancer associates in the Southeast, and the Viva Health HMO.
Located in the heart of the Southeast, Birmingham is a short drive from Atlanta, Nashville, Chattanooga, New Orleans, Memphis and Gulf Coast beaches. Some of the most beautiful suburbs in the United States surround the city. With its picturesque surroundings, Birmingham has been recognized as an
In fall 2018, UAB had a third consecutive year of record-high over all enrollment with 21,923 students, including its largest freshman class ever (2,299), with enrollment growth in every school on campus and in the acclaimed UAB Honors College. The freshman class had an average ACT of 25.2 and GPA of 3.73- both higher than 2017. UAB's students are talented and diverse, with minority students making up 40.5 percent of the freshman class and 39.7 percent of the entire of the student body. Logo Logo UAB is was recently recognized as the Top Young University in the U.S. and 10th globally in the Times Higher Education World University Rankings. UAB research expenditures are at a record high, exceeding $562 million in FY17, and UAB ranks 15th in federal funding nationally among public universities (top 4 percent) and 31st overall (top 5 percent). In National Institutes of Health funding, UAB ranks 8th among public universities (top 2 percent) and 23rd overall (top 4 percent) with more than $244 million. UAB Health system has over one million patient visits annually and is home to Alabama's largest hospital and the 3rd largest public hospital in the U.S. UAB houses the state's only level ...1 adult trauma center and the only National Cancer Institute-designated Comprehensive Cancer Center in Alabama and a five-state region. UAB is the state's largest single-site employer, with more than 23,000 employees, and has an annual economic impact of over $7.15 billion on Alabama.