Research Opportunities (Mechanistic Cancer Research) - Molecular Oncology
Scheduled Hours40Position SummaryJob DescriptionCancer is a heterogeneous disease driven by various genomic, epigenomic, and proteomic abnormalities. Though conceptually straightforward, targeting cancer-specific abnormalities proves practically challenging due to the complexity of the cellular functions of many potential cancer targets. The main interest of the lab is unravelling the biology of cancer-relevant cellular proteins with poorly understood mechanisms with the overarching goal of developing novel and more effective therapies. Currently, we are focusing on two multifunctional proteins, the actin-binding protein Profilin-1 and the AAA+ ATPase p97/VCP. Both are essential proteins with well-known functions
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