Research Opportunities (Mechanistic Cancer Research) - Oncology
Washington University in St. Louis
Location: St. Louis, Missouri
Internal Number: JR72287
We are seeking a motivated professional to join our group researching ways to improve immune cell therapies for cancer. In the last ten years, engineering of human immune cells has led to remarkable breakthroughs in the treatment of cancer. The most successful example is the use of chimeric antigen receptor (CAR)-engineered T cells to treat leukemia, lymphoma and myeloma. Our lab is focused on understanding how CAR engineering impacts normal immune cell function, developing advanced cellular engineering strategies to improve the anti-cancer activity of CAR T cells, and using principles of protein biochemistry and immunology to design more effective cancer-targeting T cells.
We use techniques from classical immunology, advanced genomics, proteomics and bioengineering routinely in our lab. This includes flow cytometry, DNA and RNA sequencing, gene therapy, CRISPR-based genome editing, analysis of human cells, analysis of blood and tumor samples from patients treated at Barnes Jewish Hospital, and protein design and synthesis.
We are a highly collaborative group looking for an enthusiastic, self-motivated, independent thinker with a tremendous work ethic to join our team. Dr. Singh is also deeply committed to the career growth and success for each member of the laboratory. Such mentorship should be intentional, planned and tailored to each member of the group thus, the laboratory operates with a primary goal of fostering career goals and development.
This position works in a laboratory environment with potential exposure to biological and chemical hazards.Â The individual must be physically able to wear protective equipment and to provide standard care to research animals.
Experience in immunology or a related field of genomics or protein biology.
Effective verbal, written and interpersonal communication skills with an ability to present on various research topics to internal or external audiences.
Ability to maintain complete and organized records and reports.
Demonstrated ability as a self-starter with strong critical thinking and attention to detail.
Demonstrated ability and knowledge of computer software and lab equipment including statistical software, spreadsheets, and lab management systems.
Ability to work in lab research environment with the ability to work well with others as part of a cohesive team, take initiative, and creatively problem solve.
Excellent planning and organizational skills.
Demonstrated abilities with the Microsoft Office suite.
Candidates with prior experience in molecular biology, biochemistry, genetics and/or cell biology with at least a bachelorâ™s degree are encouraged to apply.
If you are unable to use our online application system and would like an accommodation, please emailÂ CandidateQuestions@wustl.eduÂ or call the dedicated accommodation inquiry number at 314-935-1149 and leave a voicemail with the nature of your request.
All external candidates receiving an offer for employment will be required to submit to pre-employment screening for this position. The screenings will include criminal background check and, as applicable for the position, other background checks, drug screen, an employment and education or licensure/certification verification, physical examination, certain vaccinations and/or governmental registry checks. All offers are contingent upon successful completion of required screening.
Washington University in St. Louis is committed to providing a comprehensive and competitive benefits package to our employees. Benefits eligibility is subject to employment status, full-time equivalent (FTE) workload, and weekly standard hours. Please visit our website at https://hr.wustl.edu/benefits/ to view a summary of benefits.
Washington University in St. Louis is committed to the principles and practices of equal employment opportunity and especially encourages applications by those from underrepresented groups. It is the Universityâ™s policy to provide equal opportunity and access to persons in all job titles without regard to race, ethnicity, color, national origin, age, religion, sex, sexual orientation, gender identity or expression, disability, protected veteran status, or genetic information.
Washington University is dedicated to building a diverse community of individuals who are committed to contributing to an inclusive environment â“ fostering respect for all and welcoming individuals from diverse backgrounds, experiences and perspectives. Individuals with a commitment to these values are encouraged to apply.
Washington University in St. Louis, a medium-sized, independent university, is dedicated to challenging its faculty and students alike to seek new knowledge and greater understanding of an ever-changing, multicultural world. The University offers more than 90 programs and almost 1,500 courses leading to bachelor's, master's and doctoral degrees in a broad spectrum of traditional and interdisciplinary fields, with additional opportunities for minor concentrations and individualized programs. The faculty is composed of scholars, scientists, artists and members of the learned professions. They serve society by teaching; by adding to the store of human art, creativity, understanding, and wisdom; and by providing direct services, such as health care.