Rutgers, the State University of New Jersey is seeking a Research Associate I in Medical Oncology for Rutgers Cancer Institute of New Jersey.
The primary role of the Research Associate I (RA I), under direction of the Principal Investigator, Christian Hinrichs, is to assist with the development and application of computational genomics and bioinformatics tools based on next generation sequencing data for better understanding of cancer response and resistance to immunotherapy. The Hinrichs group has particular interest in defining the landscape of tumor-intrinsic, immune-related gene defects that mediate immunotherapy resistance. This research includes study of somatic mutations, copy number variants, gene expression profiling, tumor heterogeneity, single cell genomics, and tumor systems biology. There will be opportunities to work in an interdisciplinary team both in clinical and laboratory research settings on a variety of high impact, cutting edge projects.
Among the key duties of this position are the following:
Performs professional and scientific research in computational biology as it relates to tumor immunology and cancer immunotherapy, especially with detailed knowledge of bioinformatic workflows and genomic and transcriptomic studies. This research includes somatic mutation and copy number determination, clonal architecture analyses, single-cell transcriptomics, clonal architecture analyses, single-cell transcriptomics, development of novel genomic assays, vector insertion site analyses, complex RNA transcription studies, and real-time analysis of human genomic data as part of a clinical research team.
Participates in the daily activities of a group of professional and technical personnel engaged in research and/or testing activities.
Under the direction of the Principal Investigator, investigates, reviews, modifies, develops, and tests new analytical procedures and methodologies.
Follows laboratory rules and research protocols.
Maintains laboratory equipment and responsible for proper disposal of hazardous waste.
Interprets raw analytical data and presents and submits conclusions to the Principal Investigator for approval.
Prepares or participates in the preparation of sound, accurate reports relating to research, grant, and other activities containing findings, conclusions, or recommendations.
Functions as a scientific consultant in areas pertaining to specific expertise and trains personnel in the laboratory.
Assists with the design and conduct of research studies, according to study protocols.
Writes formal reports summarizing research work.
Minimum Education and Experience:
Ph.D. Degree or equivalent in computational biology, biostatistics, bioinformatics, genomics, or related area, plus two (2) years of related research experience.
Equivalent experience, education and/or training may be substituted for the education requirements.
City: New Brunswick
Physical Demands and Work Environment:
PHYSICALDEMANDS: Standing, sitting, walking, talking, and hearing. No special vision requirements. Lifting up to 25 lbs.
WORKENVIRONMENT: Laboratory environment. Moderate noise. Exposure to blood, excrement, antineoplastic drugs, and possible exposure to infectious and communicable diseases. Universal precautions are mandatory. Exposure to hazardous chemicals.
Rutgers, The State University of New Jersey, is a leading national public research university and the state's preeminent, comprehensive public institution of higher education. Rutgers is dedicated to teaching that meets the highest standards of excellence; to conducting research that breaks new ground; and to turning knowledge into solutions for local, national, and global communities. As it was at our founding in 1766, the heart of our mission is preparing students to become productive members of society and good citizens of the world. Rutgers teaches across the full educational spectrum: preschool to precollege; undergraduate to graduate and postdoctoral; and continuing education for professional and personal advancement. Rutgers is New Jersey's land-grant institution and one of the nation's foremost research universities, and as such, we educate, make discoveries, serve as an engine of economic growth, and generate ideas for improving people's lives.