The Center for Immuno-Oncology (CIO) of the Dana-Farber Cancer Institute (DFCI) evaluates patient samples to identify correlative biomarkers of response in immunotherapy clinical trials across many different cancer types.?? The Tissue Biomarker Lab (TBL) is a research team within the CIO that is responsible for developing and applying new analytical methods on human biopsy samples to determine the biological underpinnings of successful responses to immunotherapy through a detailed characterization of the tumor microenvironment (https://ciopath.dfci.harvard.edu/). With supervision from a Lead Scientist and Principal Investigator, the research technician will carry out quantitative, image-based spatial characterization of immune and cancer cells within patient biopsy samples.?? The research technician will be expected to work both as part of a team and independently to determine the best approaches to carry out the required analyses and to interpret resulting data
Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS and related diseases. We strive to create an inclusive, diverse, and equitable environment where we provide compassionate and comprehensive care to patients of all backgrounds, and design programs to promote public health particularly among high-risk and underserved populations. We conduct groundbreaking research that advances treatment, we educate tomorrow's physician/researchers, and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.
Perform technical procedures such as chromogenic immunohistochemistry, multiplex immunofluorescence, fluorescent in-situ hybridization, and prepare samples for advanced microscopic methods.
Develop and test new immunostaining assays, workflows and instruments for highly multiplexed analyses of cancer tissues.
Operate laboratory instruments and equipment, especially automated tissue stainers and multiplex fluorescence microscopes.
Develop and apply computer-based quantitative approaches to assess multiplex immunostained tissue samples utilizing commercial and custom image analysis software under supervision of the PI, Lead Scientist, and Lead Computational Biologist.
Keep detailed records and maintain databases containing experimental results and reagent information.
Prepare and present written or oral progress reports describing studies and results, including assembly, organization and interpretation of data.
Order chemicals, reagents and other laboratory supplies.
May demonstrate and explain various laboratory techniques to laboratory personnel, students and others.
Perform all other duties and responsibilities as directed.
At Dana-Farber Cancer Institute, we work every day to create an innovative, caring, and inclusive environment where every patient, family, and staff member feels they belong.?? As relentless as we are in our mission to reduce the burden of cancer for all, we are equally committed to diversifying our faculty and staff.?? Cancer knows no boundaries and when it comes to hiring the most dedicated and diverse professionals, neither do we. If working in this kind of organization inspires you, we encourage you to apply.
Bachelor's Degree required with a major in biology, chemistry, immunology, biophysics, or biomedical engineering preferred.
Knowledge of information and techniques related to either biology, chemistry, or medicine is preferred.
Candidates with a background or experience in computational biology and engineering are also encouraged to apply.
Experience working in a laboratory environment required.
Must have excellent communication skills (written and verbal) and be able to work with a wide variety of faculty and staff.
Ability to analyze information and use logic to address work-related issues and problems.
Must have attention to detail and be thorough in completing work tasks.
Ability to work within a team environment.
Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other groups as protected by law.
Located in Boston and the surrounding communities, Dana-Farber Cancer Institute brings together world renowned clinicians, innovative researchers and dedicated professionals, allies in the common mission of conquering cancer, HIV/AIDS and related diseases. Combining extremely talented people with the best technologies in a genuinely positive environment, we provide compassionate and comprehensive care to patients of all ages; we conduct research that advances treatment; we educate tomorrow's physician/researchers; we reach out to under-served members of our community; and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.