The Oser Laboratory in the Division of Molecular and Cellular Oncology and the Department of Medical Oncology at the Dana-Farber Cancer Institute/Harvard Medical School focuses on identifying new therapeutic targets in small cell lung cancer (SCLC). The Oser laboratory (https://oserlab.dana-farber.org/) is a highly supportive medium-sized laboratory that values mentorship and a collaborative environment for training with the goal for each research fellow to achieve their greatest potential. SCLC is a highly aggressive neuroendocrine cancer that is driven by loss of function (LOF) mutations in the tumor suppressor genes RB1, TP53, and NOTCH and high expression of oncogenic neural/neuroendocrine transcription factors including ASCL1, NEUROD1, and POU
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