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Posted: 19-Jan-23
Location: Seattle, WA
Salary: Open
Internal Number: 113194
This is a full-time Postdoctoral Scholar Fellow position on an annual, 12-month appointment with an anticipated start date of March 1, 2023. Postdoctoral Research Fellows are represented by UAW 4121 and are subject to the collective bargaining agreement, unless agreed exclusion criteria apply. For more information, please visit the University of Washington Labor Relations website. This Postdoctoral Scholar Fellow position will be based in the laboratory of Dr. Cory Simpson, MD, PhD, FAAD (Assistant Professor, Medicine/Dermatology). Dr. Simpson is a physician-scientist and a committed mentor who is aiming to build an enthusiastic research team and create a collaborative learning environment that values diversity, fosters innovation, and promotes each member's career development.
We are applying advanced methods in live microscopy and cell biology to primary human keratinocytes and an organotypic model of the epidermis. Our goals are to better understand the mechanisms of epidermal differentiation, to model genetic skin disorders in vitro, and to identify novel treatment approaches for dermatologic diseases, especially rare skin disorders lacking effective therapies.
Our lab occupies remodeled space on the new UW Medicine research campus located in the vibrant South Lake Union neighborhood of Seattle. The Simpson Lab has a dedicated spinning-disk confocal microscope, which permits us to image live 3-D epidermal cultures at high resolution and offers a laser photo-activation module for novel optogenetic approaches. We are seeking a postdoctoral fellow with experience and interest in live microscopy and image quantification methods to help us understand how organelle degradation and calcium dynamics drive keratinocyte differentiation and how they are altered in diseases compromising the epidermal barrier.
We also have access to the outstanding core facilities and collaborative faculty of the UW Institute for Stem Cell and Regenerative Medicine (ISCRM). A postdoctoral fellow with prior experience or interest in induced pluripotent stem cells (iPSC) would have the opportunity to leverage the ISCRM core for stem cell gene editing to build in vitro models of genetic dermatologic diseases. We are also aiming to engage the ISCRM high-throughput screening core to build a translational research focus with the goal of identifying better treatment strategies for rare dermatologic disorders.
The anticipated start date is Spring, Summer, or Fall 2023 with a renewable 12-month appointment.
Salary: The base salary range for this position will be: $5,459- $5,875per month ($65,508- $70,500annually) commensurate with experience and qualifications, or as mandated by a U.S. Department of Labor prevailing wage determination.
Applicants should have relevant laboratory research experience in basic molecular biology methods (e.g., plasmid cloning, PCR), cell biology methods (e.g., cell culture, DNA transfection, viral transduction, immunostaining, immunoblotting), and/or live microscopy. Experience with induced pluripotent stem cells, image analysis, and coding/computational biology would be particularly advantageous for this position. Applicants should have an MD and/or PhD degree by the start date, strong written and oral scientific communication skills, and a commitment to lab collegiality.
Applicants should apply via Interfolio.
Please submit a letter of interest, CV, and names of three references.
Please visit www.simpsonskinlab.org for more details on our research.
University of Washington is an affirmative action and equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, creed, religion, national origin, sex, sexual orientation, marital status, pregnancy, genetic information, gender identity or expression, age, disability, or protected veteran status.
Benefits Information
A summary of benefits associated with this title/rank can be found at https://hr.uw.edu/benefits/benefits-orientation/benefit-summary-pdfs/. Appointees solely employed and paid directly by a non-UW entity are not UW employees and are not eligible for UW or Washington State employee benefits.
Commitment to Diversity
The University of Washington is committed to building diversity among its faculty, librarian, staff, and student communities, and articulates that commitment in the UW Diversity Blueprint (http://www.washington.edu/diversity/diversity-blueprint/). Additionally, the University's Faculty Code recognizes faculty efforts in research, teaching and/or service that address diversity and equal opportunity as important contributions to a faculty member's academic profile and responsibilities (https://www.washington.edu/admin/rules/policies/FCG/FCCH24.html#2432).
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Disability Services
To request disability accommodation in the application process, contact the Disability Services Office at 206-543-6450 or dso@uw.edu.
COVID-19 Vaccine Requirements and Information
Under University of Washington (UW) Policy, University-compensated personnel must be fully vaccinated against COVID-19 and provide proof thereof, or receive a UW-approved medical or religious exemption. This requirement will be a condition of any offer associated with this recruitment. For more information, please visit https://www.washington.edu/coronavirus/vaccination-requirement/.
