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Position Summary:

• Treat and assess mouse models of neurodegenerative disease using behavioral tests.
• Breed genetically modified mice, perform stereotaxic brain surgeries to delivery gene therapy through viral vectors or recombinant proteins, analyze brains using morphological and biochemical assays including immunohistochemistry, Western blotting, HPLC, and q-PCR.
• Perform molecular biologic experiments that involve cloning of specific cDNAs in various vectors including viral vectors, PCR, sequence analyses, transcription assays, Western blotting, DNAprotein interaction, and cell biologic studies.
• Carry out studies with cultured cell lines, primary neurons and iPSc derived neurons.
• Conduct basic laboratory experiments in in vitro systems to study proteins and their functions.
• Analyze data, organize them and present them at laboratory meetings and major scientific meetings.
• Prepare manuscripts for publications.
• Communicate with vendors of research reagents and core facility personnel.

Minimum Education and Experience:

• A PhD and/or MD degree in Neurobiology, Molecular Biology, or a relevant science, with knowledge of neuroscience, expertise in investigations of genetically-modified mice.
• The incumbent should have training and experience in molecular and cellular neurobiology including cloning, construct design and vector preparation.
• Experience is also needed with mouse models of neurologic disease including behavioral studies, genotyping of genetically modified mice, immunohistochemistry on brain tissue, Western blotting and biochemical assays on brain tissue lysates.

City: New Brunswick

State: NJ

Physical Demands and Work Environment:

• PHYSICAL DEMANDS: The incumbent needs to be physically capable of performing the above duties, including pipetting, measuring weights and volumes accurately, standing on feet, walking to other buildings on the campus and to the animal facility. Occasionally, certain heavy items in the laboratory may need to be lifted, such as small equipment, boxes and bottles. H/She should communicate his/her research plans and findings verbally and in writing in proper English to the team and to the scientific community in presentations and publications.

Posting Number: 22ST3459

About Rutgers University

Rutgers, The State University of New Jersey, is a leading national public research university and the state's preeminent, comprehensive public institution of higher education. Rutgers is dedicated to teaching that meets the highest standards of excellence; to conducting research that breaks new ground; and to turning knowledge into solutions for local, national, and global communities. As it was at our founding in 1766, the heart of our mission is preparing students to become productive members of society and good citizens of the world. Rutgers teaches across the full educational spectrum: preschool to precollege; undergraduate to graduate and postdoctoral; and continuing education for professional and personal advancement. Rutgers is New Jersey's land-grant institution and one of the nation's foremost research universities, and as such, we educate, make discoveries, serve as an engine of economic growth, and generate ideas for improving people's lives.

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