Department/Area: Department of Immunology and Infectious Diseases
The Neafsey Lab at the Harvard T.H. Chan School of Public Health (HSPH) is seeking an early stage or senior Postdoctoral Fellow to contribute to our research program in the genomic epidemiology of malaria (https://sites.sph.harvard.edu/neafsey-lab/). Our lab generates and analyzes large genomic datasets from malaria parasites and vector mosquitoes to understand transmission patterns, demographic history, drug/vaccine resistance, immune evasion, and host/vector/pathogen interactions. In our wet lab, we generate new genetic assays for parasites and vectors, such as multiplexed Illumina amplicon sequencing panels, and we apply assays to cross sectional as well as longitudinal sample collections, driving a need for innovative approaches to data analysis. The successful candidate will work collaboratively with other group members to develop innovative wetlab and bioinformatic approaches for exploring Plasmodium malaria parasite genomic diversity. We have experimental capacity at HSPH, where we are part of a close-knit community of molecular parasitologists and vector biologists. Our lab also extends to the Broad Institute, where we belong to the Broad Institute Genomic Center for Infectious Disease and benefit from a community of expert microbial genomicists and computational biologists.
Ideal applicants will have a PhD in a relevant field, with strong background in population genetics, molecular epidemiology, statistical genetics, etc. Applicants will be expected to develop a research program that is original but fits within the general priorities of the group and funded grants, taking into account the relevant literature, own experience, and advice from other scientists. Currently funded or pending grants include: 1) projects to profile genetic diversity of infections in clinical trials of malaria monoclonal antibodies and vaccines to understand protective efficacy; 2) spatial genetic studies of parasites and vectors; 3) genome-wide screens of loci mediating parasite/vector interactions.
Candidates are required to have a Ph.D. in biology/parasitology/epidemiology or equivalent. Molecular biology laboratory skills (nucleic acid extraction, PCR, NGS library construction) are required.
Experience with next generation sequencing data analysis and statistical fluency are strongly desired. Experience in at least one scripting language and familiarity with Unix/Linux computing environments are also desired. Candidates should demonstrate a track record of consistent publication, have strong organizational, written, and oral communication skills, and should be able to work both independently and as part of a team.
Please contact Daniel Neafsey by email: firstname.lastname@example.org with CV, letter of interest, and names of at least three references.
Contact Email: email@example.com
Equal Opportunity Employer:
We are an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability status, protected veteran status, or any other characteristic protected by law.
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